<![CDATA[discussion boards — Has anyone researched SAHA?]]> http://www.cholangiocarcinoma.org/punbb/viewtopic.php?id=205 Fri, 25 Aug 2006 12:16:11 +0000 PunBB 1.4.2 <![CDATA[Re: Has anyone researched SAHA?]]> http://www.cholangiocarcinoma.org/punbb/viewtopic.php?pid=887#p887 Thank you Caroline.  Please keep us posted on AZD2171 as well.  I now must consider what protocols I may try and am trying to gather as much information as possilbe.

-Peter

]]> Fri, 25 Aug 2006 12:16:11 +0000 http://www.cholangiocarcinoma.org/punbb/viewtopic.php?pid=887#p887 <![CDATA[Re: Has anyone researched SAHA?]]> http://www.cholangiocarcinoma.org/punbb/viewtopic.php?pid=886#p886 I am looking into clinical trials for AZD2171, the new generation of Avastin.

I have a cousin who is a rep for AstraZeneca, the manufacturer of the drug, and I asked her what she could find out.

I will let you know what I find out.

-Caroline

]]> Fri, 25 Aug 2006 06:19:47 +0000 http://www.cholangiocarcinoma.org/punbb/viewtopic.php?pid=886#p886 <![CDATA[Has anyone researched SAHA?]]> http://www.cholangiocarcinoma.org/punbb/viewtopic.php?pid=870#p870 SAHA was invented by Columbia Chemistry professor Ronald Breslow and is a synthetic compound which targets tumor cells forcing the juvenile tumor cells to mature into stable cells and stop dividing.
MD Anderson lists some Phase I trials, most seem aimed at leukemia, with one where SAHA is used in conjunction with Gemcitabine targeting 'solid tumors'.

http://utm-ext01a.mdacc.tmc.edu/dept/pr … /2005-0140

Has anyone researched SAHA or know any more about it?

-Peter

]]> Tue, 22 Aug 2006 14:07:36 +0000 http://www.cholangiocarcinoma.org/punbb/viewtopic.php?pid=870#p870