Ali....tough question to answer as this disease is so individual. Some patients have terrific responses to the very same treatment that others don't.
These are the NCI recommended guidelines:
Unresectable, Recurrent, or Metastatic Intrahepatic Bile Duct Cancer
Treatment of unresectable, recurrent, or metastatic intrahepatic bile duct cancer may include the following:
Stent placement as palliative treatment to relieve symptoms and improve quality of life.
External or internal radiation therapy as palliative treatment to relieve symptoms and improve the quality of life.
A clinical trial of external radiation therapy combined with hyperthermia therapy, radiosensitizer drugs, or chemotherapy.
Check the list of NCI-supported cancer clinical trials that are now accepting patients with stage III intrahepatic bile duct cancer, stage IV intrahepatic bile duct cancer and recurrent intrahepatic bile duct cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI website.
Bile Duct Cancer (Cholangiocarcinoma) Treatment (PDQ®)–Patient Version
Treatment Options for Bile Duct Cancer
Updated: December 22, 2016