(6 replies, posted in Chemotherapy)

My husband, John, was diagnosed with cholangiocarcinoma in March 2008..stagfe 4 with metasteses to his pancreas, liverm and lymph nodes. He has been through 12 cycles of Gemcitibine...he had reduced CA 19-9 numbers after the first six treatments (from 4700 to 3300), but the numbers have gone up to 9700 and the recent CT scan shows that the tumors in the pancreas, bile ducts and liver have gotten larger.

The Dr. gave us 2 treatment options...one, to discontinue all treatment or two, to try "Folfox"...I think it is F-5U with Eloxatin (Oxaliplatin). Our insurance company has said that the Eloxatin is considered experimental for his type of cancer and has denied authorizing payment for it.

Have any of you used this chemo agent? Had any hassles with your insurance companies getting authorization for it? I think the Dr.s rational is that even though this drug is tested for colon cancer, since both colon cancer and bile duct cancers are adenocarcinomas, this might work.

Any insight or experiences would be greatly appreciated.