Now I have some more hard evidence of how the treatment has worked for me. The primary tumor in the liver is showing signs of necrosis. It has stayed about the same size, but it is less defined on imaging and not as dense. All of this adds up to a successful theraspheres treatment. Apparently, it will take several more months for all of the results of treatment to be visible but as of now it looks like it is inducing tumor death. I am hoping that it will kill of the whole thing or at least most of it and we should know that after my next scan in 3 months.
Now on to the other news of my appointments at Mayo this week. I had a stent change and that went well. My billirubin was creeping up a little bit because the stents were getting blocked and it should now resolve itself. The not so good news is that the Oncologist that I met with here believes that the cancer in the peritoneum is growing/spreading. Not a lot, but it is gaining steam. There was some evidence of this on the CT scan and some of it he is using other evidence to draw the conclusion. I was not thrilled to hear this.
My chemo regiment of Xeloda is going to get changed out. It was causing too much diarrhea, dehydration, etc. and combine that with the fact that the peritoneal cancer might be advancing and it is time for a treatment change. They are recommending Gemzar/Cisplatin. I was on Gemzar/Oxaliplatin last year and developped a reaction to the Oxali so I had to discontinue it, but it was working. I've heard that the Cisplatin is quite a harsh drug (more harsh than Oxali) so I am not looking forward to this new regiment. I am hopeful that it will be effective as it is for so many others but I am really dreading getting started with it. Right now I'm able to work a bit and feel a little bit productive and I'm concerned that starting this therapy is going to rob that from me. But nonetheless I will be getting started with it after I return from the vacation my wife and I are taking next week. If any of you have any experiences you wish to share about Gem/Cis, please feel free!!
The last piece of news from my visit to Mayo is that I also have a little bit of ascites buildup next to my liver/gallbladder. It isn't a significant amount, but it is there. I'm really concerned about this because it backs up the theory of peritoneal cancer growth and I really don't want to deal with it. So I hope that it will resolve on its' own - or at least it will resolve with chemo or diuretics.