September 4, 2015 -- Tracking liver metastases on follow-up CT scans is a critical task for clinicians, but the process is time-consuming and often inefficient. A new automated method for detecting and segmenting liver metastases may help, according to an article published online in the Journal of Medical Imaging.

Designed to operate as a radiologist would, the algorithm identifies, tracks, and segments lesions to assess changes between baseline CT exams and follow-up studies. In testing, the technique yielded high sensitivity for detecting metastatic liver lesions, in addition to a 90% accuracy rate for tracking tumors on a set of follow-up cases, according to biomedical engineering doctoral student Avi Ben-Cohen and colleagues from Tel Aviv University and Sheba Medical Center in Israel.

"The initial results presented here look promising," they wrote. "We achieved high sensitivity and high Dice segmentation results as well as a high matching rate. ... Using the [Response Evaluation Criteria in Solid Tumors (RECIST)] diagnosis criteria, we obtained a success rate of 88%. Additionally, expert ratings of the automated system segmentation results were in strong agreement."


(6 replies, posted in Good News / What's Working)

Just want to clarify....the chemo killed the nodes. Radiation next week for the tumor. I will keep you all updated.


(11 replies, posted in Good News / What's Working)

5 years WOW!! You give all of hope and inspiration!! With out you and Cathy this journey would of been a nightmare. You are a companionate mentor and have helped so many with this cancer. THANK YOU from the bottom of my heart for all that you do for so many!! ,


(6 replies, posted in Good News / What's Working)

I tried to see if I could copy a picture of my mom luck. It's been 2 years since her surgery and while the cancer has returned we are no longer living in a hopeless place. On 2 short years I have seen so much advancement with this disease that I wish anyone being diagnosed would never read old is so dated!!! People can and are living longer with Cholangio....the trick is this....BE YOUR OWN ADVOCATE!!!! doctors have old info. IF THEY ARE PUTTING YOU ON THE TYPICAL GEM/CIM... Be sure that all of the options have been well thought out. I feel that everyone needs to stay proactive and educated. This forum is the place not face book pages. Face book is great but with a limited amount of time this forum is the best resource!! So the cancer is back the chemo did work on the lymph nodes and now radiation for the tumor. Then off to Florida she goes for a couple of months of no chemo and we will hope and pray the cancer doesn't return. In the meantime I will stay on this forum watching for the latest advancements.  Mom is doing great....back to her running and picking apples with the grand kids...(I tried to upload pic....not sure it it worked:)


(2 replies, posted in General Discussion)

Anyone have any personal experience at Mass General? My moms going for a second opinion for radiation there on Thursday. She has been on Gem/cis for 3 months after a year and a half of remission. The chemo worked on the nodes but the lesion remains the same. Our hopes are that she receive radiation for the lesion and she could technically be back in remission....maybe maintenance chemo?? So off to Mass for a second opinion hoping to,get any inside info on people's experiences.


(15 replies, posted in Introductions!)

Hello Michael,

Welcome! We are from CT too. Please get a second opinion about resection! My mom had 5 doctors say no including one at Dana Farber.  Dr. Chapman at Barnes Jewish Memorial did what everyone said was not possible. You can send you scans you do not need to go in person. Nothing to loose. He is the expert at this surgery. Any questions please feel free to contact me. 860-836-2600 my name is Rosetta you can read about my moms journey under my user name Daisy

My mom is going for a second opinion at Mass General with a Dr. Jennifer Wo. Does anyone have any experience with her? Also while on the topic of Mass General can anyone offer any doctors they have had any experiences with?.

My mother had a resection late July in 2013. The 7cm tumor was removed but 3 nodes were involved. She had 6months of gemniside and was in remission till this past June ....then mom's cancer re- appeared and 2 nodes were (hot) dr's terms  and a tumor. she just underwent 3 months of gem/cim and the nodes are now clear YEAH:) but the tumor did not shrink at all. She will now have radiation to blast the tumor and then perhaps she will be back in remission (if such a thing exists) but no complaints because she was given 6 months to live almost exactly 2 years ago... And it ain't even close to over yet!!!! Hope this information helps.

May 24th that's my wedding anniversary !!! one more thing we have in common!! I now have 2 things to celebrate every year on the 24th....HAPPY ANNIVERSARY my dear sweet friend!!!!
Love you lots!!!

Posting for a friend whose account is not yet approved so she can’t post.

I'm sorry we are meeting this way but so grateful that this site and discussion board exist. Like you or a loved one, my mom was diagnosed with chlolangiocarcinoma  - sporadic hilar chlolangiocarcinoma. I want to share the details of what is known and would appreciate any information, feedback, experiences any is willing to share, especially as it relates to course of action, etc.
My mom, 65, was diagnosed last week. Based upon her MRI, ERCP, and CT angiogram, she has a mass in her bile duct, the right side of her liver has begun to shrink and the left side has started to grow. The ERCP brushing did not show cancer cells. There are signs that the tumor looks to be close to the portal vein and it might be touching it but there should be minimal involvement. Her CT came back clear so all signs show this has not spread further. Fantastic news!
We've met 4 surgeons in Manhattan in less than 1 week. All have given the same information to us. They can do a resection (YES!!) with hopes of it being a cure and there is still a small possibility this might not be cancer but we won’t know until after surgery. From reading up, I now know how fortunate and amazing my mom’s situation is for CC. We are SO grateful.     
The surgical plan is to remove the tumor in the bile duct, reattach the bile duct to the small intestine, remove the right side of the liver and 15-20% of the left, remove the gallbladder, and remove lymph nodes.
The current plan is to move forward with a resection within 2 weeks.  My mom chose Dr. William Jarnagin at Memorial Sloan Kettering.

I would love opinions on whether we seem to be on the proper path, opinions on MSKCC or just any thoughts in general. We are open to honesty and a change of plan if necessary.
Thank you all so much. Remaining positive and hopeful smile


(3 replies, posted in Introductions!)

A new friend who will be able to post in a few days asked if any one has with Dr. Myron Schwartz at Mt. Sinai. Her mother has CC at is looking at a possible resection. Another Doctor she is inquiring about is Dr. William Jarnagin. Any info on either of these doctors would be greatly appreciated. She is able to view the responses and will be able to post herself soon.


(1 replies, posted in Clinical Trials)

Has anyone heard of a phase 2 trial consisting of gemcitabean and cisplatin along with a MEK inhibitor pill trial #13004


(16 replies, posted in Members' Cafe)

You mentioned a Dr. M that Percy used...gave out his email for questions? May I have this email and a doctors name if it is still available?

I went under users....looked up Percy did not come up??

Never know exactly where to post...sorry to keep posting new topics.
My mother met with onc today in Tampa. It's been a year and a half since her resection and a year since chemo was completed.  She has had a reoccurrence. A 1 1/2 cm lesion in her liver and 3 nodes involved. The onc said that radiation can not be done because the biopsy of the nose showed it is outside the liver near the pancreas???  He said radiation was futile and said getting rid of the nodes effected was cherry picking. He wants to put her on gem/Oxi. Looking for thoughts on why no radiation??

When my mother asked was it worth it that she even had the surgery he said that it was a highly debatable topic...I said how could you debate she had a great year... No chemo, went on a cruise a happy healthy year?? Can anyone help me understand how removing a 7cm tumor was of no value. He did mention that doing so gave you hope and now what?? He said chemo is effective 25-30 % of the time?? Also said that the gnome testing is a waste because you can't do anything with the information....unless there is a trial there is nothing approved that he could prescribe?? Thoughts please

Julie what chemo did you do?

after your resection did you do chemo?

my mom has had a reoccurence after being clean for over a year. she has a 1/2 cm lesion on her liver and 3 nodes involved.

If your case is similar should you share what worked vs. not?? i will be conferenced in tomorrow on the meeting with the onc and would love to know what i should ask and be looking for. Lisa Crane as always was extremely helpful looking to see others experiences. as of not no mets anywhere else. I have been wanting radiation along with chemo but so far no one has agreed to radiation?????

When It comes to trials do you seek them out or your doctor? And the combo gem/cis has been the standard but the cis part has been debated? Any thoughts?

My mother has had a reoccurrence and I am taking a poll on those of you that have had a resection with a reoccurrence. What treatments and or surgeries did you receive? Success etc?
3 lymphs are involved and a 1 1/2 cm lesion. Any information would be greatly appreciated,

I am trying to understand that article?? Does it say that after a resection if there is a reoccurrence the prognosis is less than a year survival?? Doesn't make sense??

My mother had an MRI instead of her usual CT SCAN and they spotted a lesion and lymph nodes look suspicious as well. They will be doing an endoscopy Monday and a biopsy will be done at that time. We are pretty certain we know it's back.
My question is has anybody after a resection have a similar reoccurrence and if so were they treated with chemo or radiation?  Also the doctor MRI was done at Moffitt and our inc at Sloan said he could not weigh in on it because he has to do his own scan...they are not to open to working with other doctors. My mother is a snow bird so they do need to have a doctor in Fl as well as CT. the onc assistant at Sloan said if were so happy with our care at Moffitt why would we need Dr. Abou to weigh in on the scan? I am shocked that, that was her response.

Would like to know for those of you that are having scans done regularly… Do you have CT scans pet scans or MRI's? We usually do CT scans and today by a different doctor my mother had an MRI trying to understand why one would be better over the other?


(8 replies, posted in Hospitals)

I'm gonna give this  a shot again:) anyone in Florida have a doctor that they are currently using and would recommend?


(8 replies, posted in Hospitals)

Thank you for the info...I was wondering if anyone on this forum has a Dr. There that they have used and recommend? My mom has her scans at Sloan but I need to find a place local...I hate that she has to fly back just for a scan.