Welcome to the site. I am very sorry indeed to hear what your brother is going through right now. As Lainy says, as if he and you all don't already have enough to deal with with the diagnosis of CC, but to have the other issues as well to deal with. My thoughts are with you all right now. I am glad though that you have joined us all here as you are so in the right place for support and help and I know that you will get a ton of each from everyone here. If we can help at all then we so will.
Depression can be quite common and my dad was given prozac as well during his hospital stay, he was in hospital for around 7 weeks. Yes they can take time to work and lets hope that your brother meds work for him, and if they do not seem to be working then please try and keep on top of that. A positive attitude will certainly help you all but I know that sometimes that can be hard to maintain. As to the nutrition, there are many drinks and powders that can be added to foods to help build up weight and you will find a ton of info on these here on the nutrition board that we have on the site. It can be found here -
http://www.cholangiocarcinoma.org/punbb … .php?id=12
Ensure and procal drinks work well and my mum takes these each day. She has copd and really needs to build her weight up. There are many drinks out there and some people prefer some over others. If meals are hard to digest then eating smaller amounts more often may also be of help to your brother as well. I assume that your brother will also be on meds for his blood clots too? Warferin?
My fingers are crossed that the Folfox works for your brother. Yes it can be very hard to stay positive sometimes and you and your family have far more than anyone should have to deal with at any time. Please keep coming back here as much and as often as you want to as I know that talking can help, it certainly did for me. And know as well that you are not alone in this anymore. We are here for you, we know what you are going through and we care.
My best wishes to you and your family,