Topic: Change in treatment

I have had eight rounds of carboplatin/gemzar.  My Onc is changing it to gem only for two rounds to take stress off kidneys.  Will get a CT scan to check response.  She feels we can always go back if the results are not positive.

Has anyone had this change?  What were the results?  How did you determine if kidneys were responding?  Did you continue or go back to original chemo plan?  How fast can CC respond to a change in treatment?  Anything else of note?

Thanks in advance for your responses.

Fighting with dignity, not desperation.

Live, Laugh, Love

2 (edited by marions Thu, 01 May 2014 21:02:57)

Re: Change in treatment

Duke…..Chemotherapy is very difficult on the body hence, your platelets having been low.  I believe that physicians look at the overall response to the drugs and weigh this against possible kidney damage and  tumor resistance to the chemotherapy. ( For the later, a switch to other agents may be recommended.) 
Your physicians approach is not unusual. I hope that others will come forward and share their thoughts with you as well.
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Change in treatment

CT scan showed liver tumor still decreasing.  Continuing with gemcitabine only.  Neuropathy in toes definitely decreased.  Platelets are still hovering 100,00 to 130,000 - just high enough to allow full dose of gem.

Onc's Plan B will be to change to Folfox if/when gem is no longer effective.

Plan C will be to look for a Phase 1 trial.

Fighting with dignity, not desperation.

Live, Laugh, Love

Re: Change in treatment

Duke...fantastic news on the positive response to the treatment and decrease in regards to the neuropathy.   All looks great.  Congratulations.
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Change in treatment

Dear Duke, decreasing is great and other options definitely awesome. Keep up the good work! Thanks for the update as well.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: Change in treatment

Such good news Duke.   Glad to hear it.

Love & Hugs,
Darla

"One Day At A Time"

All of my comments and suggestions are just my opinions and are not a substitute for professional medical advice.   You should always seek the advice of your physician or other qualified health care providers.

Re: Change in treatment

Great news!

Just for today, I can get through anything.  "Never let fear decide your fate."  (from the band, Awoination.)