Topic: Gemcitabine question

Does anyone have experience with gemcitabine alone? Oncologist suggested both gemcitabine and cepcitabine post liver resection to kill off any micro cells that may be lingering. If no cancer exists wouldnt gem be enough to kill off any cells? I appreciate any input.

Re: Gemcitabine question

Lorna -
My husband did Gem plus Oxaliplatin for 6 months after his resection. I know that most often the Gem is given in combination with something else, most often I think I have seen the Cisplatin and the Oxaliplantin but there will be many more who should chime in on this.
I had pretty much the same question for our Onc in regards to the chemoradiation that we just started. Why would be want to do chemo if the cancer was gone? He said that if you think of the cancer like a weed in your yard (I think dandelions since I have so many) and they scatter seeds all over then you use a systemic weed killer over the whole yard to kill off those scattered seeds that you can't see. We are now on the chemoradiation which he equated to going back with a spot killer.
I am not sure about Gem alone but I am sure someone will answer.

KrisV

Any advice given is based on my experiences and should not be substituted for any medical recommendations. Please speak with your provider before making any changes.

Re: Gemcitabine question

Lorna....Gemzar (gemcitabine) had been a standard of treatment. The ABC-1 and ABC-2 clinical trial (UK) compared to gemcitabine alone, the chemotherapy combination of cisplatin and gemcitabine and data showed improved overall survival of patients with locally advanced or metastatic cholangiocarcinoma.  This is data reflects results of patients with detectable disease however; given the fact that we don't have any other large scale studies proven otherwise, physicians like to use this reasoning for adjuvant therapy as well. To this date we still don't have prove whether adjuvant therapy is beneficial, but we are awaiting results of some studies within this year.
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Gemcitabine question

I am not familiar with gem alone...but similar to kris's husband I have been offered the gem/ox post resection as well in case of any microscopic cells.

Hope, love, strength...2013 and for the years to come, Porter.