Topic: Interview with an Oncologist re: chemo therapy
Why are positive responses to chemo therapy so varied?
They know that in many other diseases somebody with another cancer would potentially benefit from chemotherapy.
They don't know that in CC partly, because it has not been adequately studied, partly because bile duct cancers are really very much less responsive to chemotherapy - they tend to be inherently sort of resistant to chemotherapy -.
Different organs in the body have different functions, and the bile duct sort of transports all the toxic garbage out of the liver and into the stool, and so you would expect those cells to be pretty resistant to toxins, because if they weren't, everyone else would have a screwed up bile duct.
That resistance to toxins I think, simplistically at least, makes therapy really largely ineffective.
The same mechanism that makes the cells resistant to the toxins makes them resistant to chemotherapy.
This physician did however, encourage the use of chemo therapy, although with guarded expectations. Based on his experience, many patients have had favorable results.