Topic: Chronotherapy

Has anyone had any experienc with chronotherapy-- timing the chemotherapy so that the infusion occurs at a time that the healthy cells are less susceptible to chemo and hopefully the cancer cells are more susceptible?

Here's a link to the abstract on Springerlink, http://www.springerlink.com/content/d0l420j145104340/  and there's a link on that page to the PDF version of the study.

Thanks,

G

Re: Chronotherapy

G,
thank you for posting this.  I am very interested in this.

Marion

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3 (edited by glightfoot Wed, 10 Jan 2007 19:12:58)

Re: Chronotherapy

Researching more on chronotherapy, here's a link to a mice study using Gemcitabine and Cisplatin, 
http://www.ncbi.nlm.nih.gov/entrez/quer … ;DB=pubmed -- this is not displaying the address correctly-- after the word "query" it should read ".fcgi?CMD=Display&DB=pubmed" -- so try cutting and pasting the url together.
These are the chemo drugs I am using at this time.

A related idea is having fixed-rate dose of chemo -- which could be getting chemo over a longer period of time or having an infusion pump so that they try to keep a constant level of chemo in your body. http://www.biomedcentral.com/1471-2407/5/61

G