Hello Bill&Lulu.....There had been several postings re: the FOLFIRY combination however, I don't remember the individual outcomes. It appears that since the Gem/Cis combo has become the first ever established standard of care, FOLIRY has been prescribed less often. This does not mean though, that Lulu may not show a favorable response to this combination of drugs. Bill, if you have any doubt or questions re: the recommendation of your oncologist and if you are interested in doing so, then you might want to gather a few more opinions from other specialists treating Cholangiocarcinoma.
When attending the GI ASCO in Florida I asked a similar question regarding a non-response to Gem/Cis and what then would a patient receive. The answer was confirmed by several other physicians: Then it is up to the oncologist to try other drugs in various combinations depending, on what he/she chooses.
I hope this helped.
Good luck and all my best wishes coming your way,
THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER