How common is to experience excessive fever after chemo? My mother in law is currently in the hospital because of a pretty high fever....about 102 for 24 hours after chemo this time. She also experienced a pretty high fever on her last bout of chemo, but that time they determined that it was because she was receiving it directly into her vein and she developed celluiltis. This time she has a port and no obvious signs of infection. Any advice is appreciated.