Hi Helen....Thanks so much for posting this. This great post may open the door to some hot debates.
Here are my thoughts:
Presently, only a select few are eligible for this protocol.
As far as I know, the overall survival with transplantation is significantly higher than those with resection or chemotherapy treatment.
Additionally, those PSC patients in the very early stages of this disease have been given the best chance of survival.
"The Mayo Clinic protocol involves careful selection of patients with early stage CCA which is either unresectable or arising in the setting of underlying PSC. Vascular encasement of the hilar vessels is not a contraindication to transplantation. The upper limit of tumor size is 3 cm, and there must be no evidence of intra- or extrahepatic metastases. The protocol specifically excludes patients with intrahepatic CCA or gallbladder involvement."
These are my thoughts:
Procedure is costly as are the anti rejection drugs.
The US has a significant higher rate of donors than the U K.
Life donors increasingly step forward.
I agree in that
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