1 (edited by eli Sat, 23 Jun 2012 11:54:15)

Topic: Metformin reduces ICC risk in diabetic patients

http://www.clinicalendocrinologynews.co … b1bb5.html

Metformin may do double duty in diabetes patients by decreasing their risk of developing certain types of liver cancers in addition to reducing their blood sugar, studies have shown.

Treatment with the glucose-lowering drug was associated with a nearly 60% reduction in the risk of intrahepatic cholangiocarcinoma (ICC) among diabetes patients in one study presented at Digestive Disease Week 2012

What I wonder after reading this article:

If metformin reduces the risk of ICC in diabetic patients, maybe just maybe it can reduce the risk of recurrence in CC patients whose disease is in remission?

Re: Metformin reduces ICC risk in diabetic patients

WOW! Eli, I was on Metformin for a few years and thought it was giving me the runs a year ago and so my Doc switched me to Insulin. Now after a year I truly believe that it was not the Metformin but the Ulcerated Colitis coming on. Going to talk to him when I see him in August. Thanks so much for this.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

3 (edited by PCL1029 Sat, 23 Jun 2012 13:06:59)

Re: Metformin reduces ICC risk in diabetic patients

Hi, Eli,
I did read this article twice. If your wife or  patients have a hx of diabetes, it definite worth to try it on, it is much better than statins ,you know.the one that we discussed .if the patients are diabetes, definitely ask the doctor for it if no contraindications . Meteor min is generally a very safe drug with much less side effects than other diabetes medications.
But if patients are not diabetic  and their lab( the glucose) q normal, then it may not be a good idea unless the patients knows very WELL about hypoglycemic  symptoms so they can prevent fainting or other side effects as the result  of low blood sugar. In some way, it may required immediate treatment such as glucose infusion or at least a quick glass of orange juice.
God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Metformin reduces ICC risk in diabetic patients

Lainy, you are welcome. Note it's not just ICC. They also found that it reduces the risk of hepatocellular carcinoma (HCC).

Re: Metformin reduces ICC risk in diabetic patients

Thanks for this piece Eli!

Gavin

Any advice or comments I give are based on personal experiences and knowledge and are my opinions only, they are not to be substituted for professional medical advice. Please seek professional advice from a qualified doctor or medical professional.

Re: Metformin reduces ICC risk in diabetic patients

Hi Percy,

Thanks for the words of caution about hypoglycemic symptoms. My wife is not diabetic or even pre-diabetic, so I agree it's probably not a good idea to put her on Metformin.

Speaking of hypoglycemia, my wife takes maitake mushroom extract on a regular basis. As you know, maitake mushroom lowers blood glucose in many patients. It definitely seems to have that effect on my wife. She had to stop maitake during chemo, because our oncologist was worried about low blood glucose. She restarted maitake after she was done with chemo. If hypoglycemic effect reduces the risk of relapse, and that's a big IF, I hope she can get it from maitake.

Best wishes,
Eli

Re: Metformin reduces ICC risk in diabetic patients

Hi,Eli,
I took the maitake  mushroom  36 drops  twice daily after my first resection.
But after my second resection, I dropped it from my list. I do not think it xworks for me. Now I , after my second resection, I switch to take 4-5 ONCOZAC ( yunzhi extract) capsule twice a day to replace my complimentary medications. I do not know whether it works until the next resection comes, if it can prolong the time for resection (> 24 months or more) then I will continue to use it ,of course if the cancer never returns because of God's Grace, then I will use it forever.
God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.