Topic: New member
My husband was diagnosed the end of May 2012 with hepatocellular and CC Stage IV. Within one week we learned of the mass and found it had penetrated his bones and lymph glands in the abdomen. The right arm was moth eaten from the cancer and eventually broke despite efforts through radiation to prevent this from happening. He now has a rod in his arm and is undergoing PT to help him regain use of his arm. He has gone through eight cycles of Gemzar/Cisplatin. It started to affect his blood and he has gone through numerous transfusions of red blood cells and platelets. The end of February he was in the hospital for 8 days as the platelets were down to 3 and they were having difficulty getting them back up. His doctor then put him through 1 cycle of 75% strength Gemzar as tests revealed the kidneys were being affected by the Cisplatin. She then decided two weeks ago to change the chemo to Docetaxel and give him a shot of Neulasta. His lab work came back yesterday and showed the WBC at 43 (unusually high) and the AFP tumor marker at 1844 as well as some other abnormalities. He is very discouraged. The last PET showed no evidence of cancer in the bone or lymph glands and the mass in his liver was a little smaller. This was done in December. We went in October to Johns Hopkins for a consultation and were told that surgery was not an option due to involvement with the hepatic portal vein. This last bloodwork showing the increase in the AFP tumor marker from 1139 to 1844 is quite disturbing. When he was first diagnosed the tumor marker was 2452 and based on treatments with Gemzar/Cisplatin it had dropped to 972. Has anyone had any experience with Docetaxel?