Topic: IRE (Irreversible Electroporation ) To Treat Tumor Near difficult Area
Below is IRE treatment model in Human.(April 14-18 2013 Society of Interventional Radiology Convention.)
for a more deeper approach.click the link below.(very easy to understand:
and choose the slide presentation on this subject.(2013 SIR Annual Scientific Meeting Press Releases: Sunday, April 14)
Electrical pulse treatment pokes holes in hard-to-treat tumors;
New minimally invasive therapy safely treats complex cancers, leaves healthy tissues intact
Below is an older info but still useful in understanding IRE in animal model.
We observed cell ablation to the margin of the treated lesion with several cells thickness resolution. There appears to be complete ablation to the
margin of blood vessels without compromising the functionality of the blood vessels, which suggests that IRE is a promising method for treatment of tumors near blood vessels (a significant challenge with current ablation methods). Consistent with the mechanism of action of IRE on the cell membrane only, we show that the structure of bile ducts, blood vessels,
and connective tissues remains intact with IRE. We report extremely rapid resolution of lesions, within two weeks, which is consistent with retention of vasculature.
We also document tentative evidence for an immunological response to the ablated tissue. Last, we show that mathematical predictions with the Laplace equation can be used in treatment planning.
The IRE tissue ablation technique, as characterized in this report, may become an important new tool in the surgeon armamentarium.--www.tcrt.org
I believe it is using in human now in trials.