Mary..... This is a difficult disease to treat and no magic bullet has been found as of yet however; treatment options are available and some provide excellent results. You have done everything right by informing yourself about this disease and making educated decisions while working with experienced physicians.
Also I would like to mention that the criteria for the above mentioned clinical trial is not very restrictive, as it requires disease nodules size and occurrence limits fitting the parameters of the proton beam radiation machine and tumor biopsy. The later is required for all clinical trial participation.
I am not advocating for your enrollment in this trial rather I would like to point out that the path for treatment can be addressed in numerous way. Ultimately it is the physician helping you understand and guide you. Please, don't doubt yourself.
•Biopsy proven unresectable or locally recurrent hepatocellular cancer or intrahepatic cholangiocarcinoma. Patients with a single lesion must be 12cm or less in greatest dimension. For patients with two lesions, no lesion may be greater than 10cm in greatest dimension. For patients with three lesions, no lesion may be greater than 6cm in greatest dimension. Patients may have single or multinodular tumors (up to 3). There must be no evidence of extrahepatic tumor. Portal vein involvement or thrombosis is allowed.
•Participants must have measurable disease, defined as at least one lesion that can be accurately measured in at least one dimension (longest diameter to be recorded) as 20mm or greater with conventional techniques or as 10mm or greater with spiral CT scan.
•Patients may have had prior chemotherapy, targeted biological therapy, surgery, transarterial chemoembolization (TACE), radiofrequency ablation, or cryosurgery for their disease as long as it is greater than 4 weeks from first protocol radiation treatment (6 weeks for nitrosoureas or mitomycin C). Patients may not have had prior radiation to the affected area.
THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER