Topic: Safety alert issued by FDA with the use of Tarceva

I came across the following alert:
It can be found on http://www.hemonctoday.com/article.aspx?rid=31571

OSI Pharmaceuticals Inc. and Genentech Inc. issued a safety information letter for erlotinib (Tarceva) after the results of a pharmacokinetic study revealed cases of hepatic failure, hepatorenal syndrome and fatalities. Erlotinib is used in the treatment of non

2 (edited by JeffG Tue, 30 Sep 2008 14:07:10)

Re: Safety alert issued by FDA with the use of Tarceva

RANK----- Thank You so much for your post.  It confirms my suspicions of another chemo drug, or at least in my own personal feelings, that I had, of it making matters worse for my liver.  I just saw my Oncologist on Thursday and he asked if I was going to try anymore chemo after radiation?  I said I might.  He suggested Tarceva.  I said I'm not taking that one.  He asked why? I told him it has not been getting very good reviews in my opinion.  So he suggested carboplatin again, as I wasn't on it that long back in 05.  Thanks again for being so alert and posting this safety notice.

God Bless,
Jeff G.

Take it to the Limit,One More Time! (Eagles)

Re: Safety alert issued by FDA with the use of Tarceva

Just one other note on Tarceva. My mom was on it for about 3 months and she developed a serious problem breathing. It caused inflammation in her lungs. They admitted her to the hospital on Monday and put her on a ventilator. She is beginning to do better now and hopefully will come home in a few days. This is something that only 5% or so of the people develop (or so they say) but something important to watch out for.

Dawn

Re: Safety alert issued by FDA with the use of Tarceva

I'm sorry to hear about many people having side effects from Tarceva. Maybe my case is unusual, but I have had no side effects, and have been on it for 6 months. My tumors continue to be stable; no growth at all.

Violarob in Texas

Re: Safety alert issued by FDA with the use of Tarceva

Violarob in Texas---- It goes along with what we have always said; different chemo works differently on different people.  We are all so unique and individual. 
Jeff

Take it to the Limit,One More Time! (Eagles)