Topic: Clinical Trial at Penn

A new clinical trial using gemcitabine, ironotecan and panitumumbab (a human monoclonal antibody against epidermal growth factor) has just started at the University of Pennsylvania. I am patient # 1 - and have very advanced AND metastatic disease (on imaging studies) and am on narcotics for pain though my liver function tests are holding up. I was in incredible health before this happened three months ago so maybe that has helped - plus I am determined to live long enough to get my children (15 & 17) through HS as I am already a widow .  Anyway, although there is something else, I think, going on for me as I actually had some tumor shrinkage earlier than expected (after only one week of chemo) and have been megadosing with 50,000 IU Vit D a day, 1000 mg resveratol, and around 3 fish oils a day, I was told by a number of  doctors I spoke to (including at Sloane Kettering and Pittsburgh) that this is a great trial (I am a doctor as well, BTW).  Insurance will cover the first two drugs but not the panintumubab  - which is being supplied by Amgen. Anyway - I will keep you all posted but I wanted to let you know about this.  My physician is Nevena Damjanov (Nevena.Damjanov@uphs.upenn.edu) and I have been immensely pleased by her care.  Anyway -- if you are interested I would contact her .............. Elizabeth

PS - I would also consider the supplements I am taking - see the website for the Vitamin D council. Even though there isn't data for CC some of the date for other cancers is encouraging ...... certainly led me to give it a try.

Re: Clinical Trial at Penn

Hello Elizabeth....How nice to hear from you.  I wish for continuous success with shrinkage of the tumor and for you wellbeing to continue as is.  Also I wish for many more postings with equally exciting good news. 
Thinking of you and sending many hugs your way,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Clinical Trial at Penn

Best of luck on the trial. My doctor was debating between panitumumbab and avastan for me and I ended up with Avastan. I think it has something to do with which type of enzymes your tumor produces as to which one is better. I got Avastan as the sample of my tumor taken during surgery wasnt sufficient to know for sure which type I had. So I am very interested in how panitumumbab will work. Keep us posted. I was also researching ironotecan and was thinking about asking my doctor about but I forgot so thanks for the reminder.

Best of luck and get some more tumor shrinkage!
Kris

Cancer is a word, not a sentence.

36 year old patient with buckets of hope

Re: Clinical Trial at Penn

Elizabeth, that sounds like wonderiful news!  I studied a ton about naturpathy when my dad was diagnosed and Vitamin D kept coming up in my studies.  Infact the hospital we were at(Cancer Treatment Center Of America) prescribed Vitamin D along side his chemo treatment.  That didn't last too long for us, because he couldnt' tollerate the chemo(xoleda) and/or anything else he was being given, so we stopped the Vitamin D shortly after he started.
I wish you continued success!!
Peace
Barbara

The  Lord is my shephard