Topic: OXALIPLATIN

Has anyone had any experience with this Chem o drug.
My husband has had 3 bouts of this so far. He has been on Chem o with Gemzar and Zeloda pills for the last year and a half and has become immune to it. Dr put him on oxaliplatin and Zeloda pills 3 bout ago, he has one week on and one week off.
He is not as sick as he was on the Gemzar and Zeloda. He is functional and able to drive our daughter home from school.
Which he could not do when he first received the Gemzar.

Re: OXALIPLATIN

Dear Oscarcamacho243   After surgery, I received both gemzar and Oxaliplatin by infusion (every 2 weeks, for 5 months). Of the two, the Oxaliplatin, a platinum based drug,  had the most intense side effects(nausea, exhaustion, coldness of extremeties and ultimately peripheral neuropathy). I madi it through, but it was really tough. It sounds like your husband is taking it better than I did. Kudos. Keed doing what you're doing.

Re: OXALIPLATIN

I took three rounds of Gemzar and Cysplatin--which did not help--and I tolerated those very well. I am currently on Oxy (day 1) and Xeloda (Twice daily for Day 1 through 14).  Like Michael I am experiencing coldness of extremities, exhaustion, dry hands and bruised feet.  The Xeloda tends to turn my stomach unless I drink a boatload of water.

After two days home,  I can function and return to my office job and live a relatively normal life even if I am not the energizer bunny and need to rest regularly.

Re: OXALIPLATIN

Hello jsratlanta.....thanks for coming on board.  And thanks for jumping right in and sharing your knowledge.  It is very much appreciated.

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: OXALIPLATIN

Like Michael from San Diego stated, it is the oxaliplatin that is the cold sensitive part of the regiment. It is the only drug to have such cold sensitizing side effects. I have made my share of mistakes with it. Take things slow when ingesting liquids. You don't want to end up in the ER.

Re: OXALIPLATIN

I have now had 8 rounds of Oxy and Xeloda (12 PILLS A DAY)and the cumulative fatigue and neuropathy is more profound but I am still working part time.  Hanging tough,  my CA 19-9 levels have reduced from 508 to 208.  So it is encouraging.

Re: OXALIPLATIN

jsratlanta.....congratulations on your great response to Xeloda - Oxyplatin mix.  How many more treatments are you looking at?  Is the perihipial neuropathy more tolerable at this time? Certainly, the tumor count is so very encouraging and I am wishing for it to continue to spiral downward.
Hugs
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: OXALIPLATIN

jsratlanta,
I will be starting the same combo on Wednesday. I am so glad you are responding so well to it. May your numbers continue the downward descent!

Kris

Cancer is a word, not a sentence.

36 year old patient with buckets of hope

Re: OXALIPLATIN

jsratlanta...my husband was on oxyaliplatin and a cocktail of two others...the oxy made him EXTREMELY sensitive to cold....everything he ate and drank had to be warm...bath time had to be very, very hot water and the thermostat had to be on throughout the house at close to 80...our dear friends bought him a flannel heated blanket...he just never seemed to be able to stay warm...just a little heads up...all people are different and their responses to treatment as well...but if you can prepare ahead of time...if and when symptoms occur...it is less stressful...another thing...it seemed to bother his stomach a whole lot more...so vomiting was something he did often...I always had paper towels and a wastebasket with a liner right beside him....know that you will be in our prayers as you begin yet another avenue in fighting this horrible, awful beast.

Love,
Heather

Re: OXALIPLATIN

I get to have my cell poison (oxaliplatin) today.  Yippee!  (NOT!)

Re: OXALIPLATIN

Lisa, can't you tell them you would rather have a Martini? Lots of luck and hugs...

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: OXALIPLATIN

Lainy wrote:

Lisa, can't you tell them you would rather have a Martini? Lots of luck and hugs...

I get my first round of poison tommorrow...so Lainy, I will try your suggestion and ask for a margarita (frozen) and see if it works.

Cancer is a word, not a sentence.

36 year old patient with buckets of hope

Re: OXALIPLATIN

OW!!!! Stay away from the cold stuff!

Re: OXALIPLATIN

Yea! You will get brain freeze along with chemo brain!!!!  You girls are tooooo much.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: OXALIPLATIN

OW!  feet hurt!  pins and needles!

Waahhh.

Good luck, Kris!  Hope you come through it better than I did.

Re: OXALIPLATIN

Good luck with the chemo.My sister started chemo today for a different cancer so supportive vibes to all
       Janet

Re: OXALIPLATIN

Dear Oscarcamacho243,

My Mom (77) had 5 rounds of Oxyliplatin and Gemzar each two weeks apart.  She was amazing and had absolutely no side effect except for the cold neuropathy that lasted two days after each treatment.  She was mostly miffed that it curtailed her having her milkshake on those two days.  I was amazed that she never experienced anything bad with these two drugs.  She also later added Nexavar to the mix and then proceeded to the Xelolda.

Just remember everyone is different in their tolerances and this monster of a disease is different for everyone as well.

I hope for the best for you.  You and your family will be in my thoughts and prayers.

Hugs!

Pam

My Mom lost her one year battle with CC on April 3, 2009.

"A prognosis is simply an audit of how truly precious each day is.  Live each day to the maximum, celebrate what was, and what is - Don't spend your life looking forward to what will or might be." .... words of wisdom from my beloved son on hearing of his grandmother's CC prognosis.

Re: OXALIPLATIN

After 7 months on Oxy, the neuopathy got so bad--no feeling in my hands to the second knuckle--they had to take me off it.  I am still on Xeloda, which I tolerate very well, on its own.  Good luck!

Re: OXALIPLATIN

I really don't like Oxy although it seems to be working for me.  I miss my ice cream and cold milk.