Topic: Dad's disease progression

Hello everyone -

I am an infrequent poster so I will give brief history. My dad (64) was diagnosed with CC almost a year ago. He was diagnosed through cell brushing because there was no clear visible mass; he was however jaundiced and had back aches but after a stent was placed these symptoms reduced. In a subsequent biopsy it was determined he also had lung mets so resection was not an option. In September he started with Gemzar and did OK until he caught a severe infection in Dec. He resumed Gemzar about 4 weeks ago and had been OK again.

Today he went to the Dr. and they still see no clear mass in the region although there is some debate about his pancreatic head having a deformation - though not a clearly visible mass. Also, some of his lungs appear to have grown slightly and he also has some new ones. The Dr. Changed the regimen to Xeloda and he will start on Monday. I know many have experience with Xeloda so any experiences will be greatly appreciated.

I am really concerned about the pancreatic imaging. Has anybody had any similar experiences? At some point it was even thought the cancer might be pancreas and not CC but several Dr's have discounted it. All claim that with T4 pancreatic cancer he would not have survived this long.

Also, does anyone have experiences with lung mets and expected progression or known complications?

Overall he is doing quite well albeit being very tired and after the infection very cautious.

If anyone can share experiences it would be great.

Thank you and best of luck to all.

Amilcar, Seattle WA

Re: Dad's disease progression

My husband also was diagnosed with intrahepatic cc in July of 06 and was seen at Northwestern and Mayo.  Their only recommendations were chemo for the rest of his life and he did not want the side effect so we did nothing until this month.  Now we are in Mesa Az doing an alternative treatment of Insulin Potentiation Therapy where they use insulin to open up the cancer receptors and then infuse 10% of the normal chemo dose so it goes directly to the cancer.  Joe has had no side effects but we won't know if this is working until he has had 6 weeks of it.  He is on his third week.  it is not covered by medicare as far as we know and is very expensive but we will see if it is worth it.  It is an alternative and a lot of people dont' believe in it.  A raw vegan diet also is used in conjuction with it.  The docotr is Dr. Thomas Lodi and he has a website if you are interested.  Everyone has to do what they think is right and what the patient can tolerate.  We prayed hard for wisdom in our decision and we willl just have to wait and see. Joe still feels really well and has no surgery, stents etc.  Good luck with whatever decision you make.  This is a tough road but we are trying to focus on the wellness inside that is trying to beat this.  God Bless  Mary Anne

Re: Dad's disease progression

I forgot to say that his cancer has metastized to hisliver and 5 spots in his lungs so he is Stage 4.  The most recent pet scan showed there are no new areas.  This was done just before we started treatment here.  mary Anne

Re: Dad's disease progression

My husband took Xeloda for three months, Sept - Dec 06.  He didn't have excessive nausea, and what nausea he did have was probably because of the diseased liver.  He didn't lose his hair although his hair thinned a little.  The main side effect was the irritation and peeling of his hands and feet.  He would do two weeks on the pills and one week off.  The first sets weren't much different in the way he felt, but by the time he got to the last batch of pills, he was really tired.  But overall, he didn't have a harsh experience.  Xeloda had no effect on his liver tumor though.  But he still thought it was worth trying.  I've read some people say Xeloda was harsh, but he didn't experience it that way.