In case anyone is wondering, this may be the abstract bosco references above. (although I'm not completely certain)
http://www.asco.org/portal/site/ASCO/me … ctID=33382
Bosco - I think you hit on a question that many patients face - which regime to choose? I do not feel like it is my place to comment on which regime to choose, as this is an incredibly personal decision with no right/wrong answer. However, I'd like to make a comment regarding clinical trials due to some misconseptions that seem to exist. First, I think clinical trials are fantastic. Without these trials, there will not be advances in the treatment of cholangio. The researchers that run these trials are relentless at finding positive results, and I believe they will find a good treatment.
My only comment pertains to the purpose of a clinical trial. The underlying purpose is to answer the hypothesis posed by the researcher. However, there is sometimes a perceived purpose from the patient's perspective that the clinical trial presents a means of providing a cure, or at least a reduction in tumor growth, for an individual patient. Now, this result may very well flow out of the clinical trial, and the individual patient may see positive results. But what I'm getting at is that the clinical trial is not being presented for the purposes of treating one patient. Rather, it's being offered to try to answer a question that applies to many patients. So, I would keep that in mind when evaluating clinical trials.
I know that doesn't really help you with advising your sister. My best to you both as you evaluate the options and decide on the next course of treatment. I will keep you both in my thoughts and prayers.