Topic: Help re targeted therapies (NYTimes articles 2/21 and 22/2010)
Has anyone read the NYTimes articles about a targeted cancer therapy trial phase 1 for melanoma?? (Third and final one in series coming tomorrow, I think)
It is about a doc who dropped his oncology practice to develop BETTER drugs for cancer.He chose melanoma and found a protein that results from a disrupted gene and promotes melanoma. What to me is so fascinating is that when this drug works it is effective on highly advanced cases, patients with many many metastises.
Clearly it is only phase 1. And patients are getting "only" life-extension- but to see people on death's door-step regaining their health for 9 good months is really amazing.
My question is: does anyone know of any trials or palliative uses of drugs that work on choalngiocarcinoma's pathways? I doubt there are any in development specifically for chaolangio due to its tiny market... But maybe some already approved for other cancers? Or in trial for other cancers that are available to stage IV cholangio patients?
Also, has there been any work done on the genetic mutations that show up on cholangio patients?
We are inspired to look for answers!!
Best to all.