My 36 year old brother was diagnosed with cholangiocarcinoma in August of 2005. They thought he was a good candidate for resection; however, when they opened him up, they said they tumor was around an artery and could not be removed. A stent was put in his bile duct and, since the surgery, he was on a chemo regimen of gemcitabine and cisplatin followed by seven weeks of radiation. Things appeared to be going fairly well based on the initial follow-up PET scans and tumor markers with a few set backs. Last week his PET scan revealed tumor growth and they started chemo again, adding Avastin this time. He had a visit this past week with the doctor who did the stent placement and was told the tumor appears to be wrapping around the intestine. I would appreciate any suggestions/tips/advice for specialists, treatments, alternative treatments, etc. He lives in Flagstaff, Arizona and has been going to Tucson for treatment. Everyone's stories on this site helps you to not feel so alone in this mess! Thanks!