Hi, Lesley,
It helps in a way that I know what to ask for the pathology dept of the hospital to have the " unstained "slides and the thickness of them. But Lesley, I think we both are thinking too far ahead of the biomarkers technology.
I don't think most of the lab can do "unfrozen cut" of the tissues submitted by the surgeon. I think the specimens must be frozen to be solid enough for cutting.
This time due to the pathology report indicated there are only focal atypical ductal epithelium and no definitive carcinoma identified.Therefore after talking to the doctors;we both agree we will not do the biomarkers for chemo-sensitive testing .
The EGFR,VEGFR1,VEGFR2 RRM1 and ERCC1 were suggested by my oncologist but he indicated there are no consensus or criteria or protocol among the oncologists to really look into them and use them to the best way they should and the sensitivity of each test is not well standardized .
In short, these kind of testing may be a few years head of its time.
The following is copied from Gavin's research on the "Web Forum",take a look at it and you will have a better idea about this kind of testing.
Again, if we all work together and contribute our share,I believe the next 5 year will be very exciting in CC research.
God bless.
GWU Researchers Awarded $500K by NCI to Develop Biomarkers for Bile Duct Cancer
June 16, 2011 it the link will not work,just go to the "web forum" look for Gavin's June 17 entry title (GWU-------);and you will find it.
http://www.genomeweb.com/proteomics/gwu-researchers
Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.