This side effect may be dose limiting; ,76%;acute 65%;persistent 43%.
"Two different types of neuropathy may occur;First,an acute(within 2 days),
reversible (resolves within 14 days),with primarily peripheral symptoms that are of exacerbated by cold ; avoid mucositis prophylaxis with ice chips during oxalipation infusion.
Secondly, a more persistent(>14days) presentation that often interferes with daily activities (ie: writing,buttoning swallowing), these symptoms may improve upon discontinuing treatment.---from drug information handbook 16th edition,APHA.
Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.