• Jane
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  • Registered: Sun, 17 Apr 2011
  • Posts: 3

Topic: Fulfox - has it worked for you?

I have a question.....has anyone not responded to gemzar-cisplatin and gemzar-xoloda but did respond to fulfox.  My mom was diagnosed last June (2010) and has tried both treatments with no success.  She is trying to decide if it is worth trying the third line of defense - fulfox.  Please share your success stories.......
Jane

  • From: Phoenix AZ
  • Registered: Fri, 13 Jan 2006
  • Posts: 8,218

Re: Fulfox - has it worked for you?

Hi Jane and welcome to our wonderful family. Just a suggestion, if you go to our Search Engine at the top of the page and type in Fulfox I know some posts will come up reagrding that treatment. I also know you will be gtting some answers here as well. Best of wishes to your Mom.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.
  • Jane
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  • Registered: Sun, 17 Apr 2011
  • Posts: 3

Re: Fulfox - has it worked for you?

I am grateful to have this resource, thank you.

  • From: Revelstoke BC
  • Registered: Sat, 01 Jan 2011
  • Posts: 552

Re: Fulfox - has it worked for you?

Hi Jane,  Sorry I do not have any information on Fulfox, but you are the 2nd person to ask in the last couple of days which I find interesting. Maybe it is something they are using more? Let us know what you find out about it. Wishing you and your mom success. Nancy

Loving my husband from afar.

5 Reply by ca_paul (edited by ca_paul Mon, 16 May 2011 22:16:35)

  • Registered: Mon, 16 May 2011
  • Posts: 14

Re: Fulfox - has it worked for you?

Hi,
My brother was on the GEMZAR-cisplatin regimen since his diagnosis of intrahepatic CC on 4/13.  After 1 round, his CA19-9 results came back at 24000 vs 17000 before the start of chemo.
He feels good and has minimal side effects during the chemo, but from the CA19-9 results, it seems to not be working.
His doctor will take schedule an immediate CT scan and will switch to GTX next. 
He also mentioned Folfox too, so we're also interested in response that others may have from this relatively different chemo cocktail.

Thanks for your inputs.

Love for my brother.  Being grateful for everyday.
  • Registered: Wed, 29 Jun 2011
  • Posts: 9

Re: Fulfox - has it worked for you?

I started on Gem/Cis and experienced tumor growth. We changed to Folfox in July. My scan at the end of August showed no change in tumor from June (stopped the growth). My CA19-9 has dropped dramatically since July & we are expecting tumor shinkage when I get my next scan on Oct 24th. My liver function has returned &  I have not taken any pain medication in over a month. I will update after my end of month scan, but it seems to be working.

Mike

  • From: Phoenix AZ
  • Registered: Fri, 13 Jan 2006
  • Posts: 8,218

Re: Fulfox - has it worked for you?

Mike, no growth is excellent and suspecting shrinkage even more excellent. Pleae do keep us posted on your progress and much good uck!

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.
  • Registered: Fri, 12 May 2006
  • Posts: 8,174

Re: Fulfox - has it worked for you?

Mike.... Often times a switch to a different chemotherapy protocol shows the kind of results you are experiencing.  This is fantastic news. Can't wait for your update
All my best wishes,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER
  • Registered: Wed, 29 Jun 2011
  • Posts: 9

Re: Fulfox - has it worked for you?

We have also started on some suppliments which include the following: Vite E, Beta Carotene, Curcumin ( active ingrednt in Tumeric), Fish oils.  For those that do not now what Fulfox is it contains the following regimen of drugs: Oxaliplatin, 5FU and levoleucovorin.  We had started on Gem Cis and had virtually no side effects but as others have noted our CA19-9 jumped while local lymphnodes apeard to respond it appearded as though that found in the liver did not.  We have had one scan since on the current regimen which documented stable disease.  During the last month our CA19-9 dropped dramaticly ( this is also the time frame we started these supplements).  Best regards,
Linda

  • Registered: Wed, 29 Jun 2011
  • Posts: 9

Re: Fulfox - has it worked for you?

Well got the results from our scan. No shrinkage, but no growth either. Tumor markers have dropped again and blood values are in normal range. Liver function is good......maybe on the way to gaining some ground. No growth is good since first Dr gave me 3 months back in April.

Mike

  • From: Phoenix AZ
  • Registered: Fri, 13 Jan 2006
  • Posts: 8,218

Re: Fulfox - has it worked for you?

Good, good, good news, Mike. You may be on to something here!!:):) Please keep us posted, you know we care.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.
  • Registered: Fri, 12 May 2006
  • Posts: 8,174

Re: Fulfox - has it worked for you?

Mike....stable has taken on a new meaning when dealing with this cancer.  Good news all the way around.  Thanks for sharing.
All my best wishes,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER
  • Gavin
  • Gavin
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  • From: Scotland - Dundee
  • Registered: Tue, 23 Sep 2008
  • Posts: 4,832

Re: Fulfox - has it worked for you?

Hi Mike,

Thanks for sharing your news with us all here. No growth and stability is good news! And your liver function news is also good to hear as well! Hoping for the good news to continue for you and looking forward to hearing more from you. Please let us know how everything goes.

Best wishes,

Gavin

  • Registered: Wed, 29 Jun 2011
  • Posts: 9

Re: Fulfox - has it worked for you?

Latest update: had another scan yesterday. Main tumor shrank by 2cm, some of the lesions in the right side of my liver have disappeared. Read the full report from the Dr that she emailed my wife today & found out that my portal vein involvement has shrank as well......WHAT A CHRISTMAS PRESENT!!!!

Mike big_smile

  • From: Phoenix AZ
  • Registered: Fri, 13 Jan 2006
  • Posts: 8,218

Re: Fulfox - has it worked for you?

Mike we LOVE the good news! Not just a great Christmas present but what a way to start the new year!!! CONGRATULATIONS!

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.
  • Gavin
  • Gavin
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  • From: Scotland - Dundee
  • Registered: Tue, 23 Sep 2008
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Re: Fulfox - has it worked for you?

Hi Mike,

Thanks for sharing this, this is great news indeed!!! The best Christmas present indeed and a great end to the year! Looking forward to hearing more good news from you in 2012!

Best wishes,

Gavin

  • Registered: Fri, 12 May 2006
  • Posts: 8,174

Re: Fulfox - has it worked for you?

Mike...Incredible, encouraging, uplifting and the perfect way to end the year 2011.
All my best wishes,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER
  • From: Uniontown, Ohio
  • Registered: Fri, 23 Sep 2011
  • Posts: 1,488

Re: Fulfox - has it worked for you?

Mike- So happy for you. Awesome news.

-Pam

Hoping for a miracle for my daughter, Lauren.

My comments, suggestions, and opinions are based on my experience as a caretaker for my daughter, Lauren and from reading anything I can get my hands on about Cholangiocarcinoma. Please consult a physician for professional guidance.

Pamela's Website