Topic: Xeloda (oral) Questions

So I am just starting my 2 of 6 cycles of oral xeloda. I take 1650mg twice a day for 14 days with a week off. I haven't had much in the way of nausea, not needing to take any meds. I haven't had any severe diarrhea, which is also good. I noticed that towards the end of my first cycle I got painful hand and feet. Not the red and cracking hands that some people get. I also have a lot of fatigue, much more with this than the gem/cis IV. Wondering if  anybody has any tips to help with side effects. Thanks.
Shari

Re: Xeloda (oral) Questions

Shari, I am just starting Xeloda this weekend, 1500mg twice a day for 14 days out of 21.   I might be looking for side effect tips also.  Along with the Xeloda, I will also be receiving my first treatment of Irinotecan tomorrow.  I am really nervous about this treatment plan.  I have been receiving FUDR in my liver infusion pump for 4 months with zero side effects.  Prior to that, I was receiving a treatment of Gemzar with slight side effects that lasted about 36 hours. 
Best wishes to you!

Cindy

3 (edited by eli Fri, 02 Dec 2011 08:54:07)

Re: Xeloda (oral) Questions

Xeloda is an oral form of 5-FU. My wife was on infusional 5-FU for six weeks.

Here's a tip that we saw too late. I wish we knew it on Day 1.

If you have thick, hardened skin on the soles of your feet, get rid of it now. If you are unlucky to develop a really bad case of hand-foot syndrome (like my wife did), that thick hardened skin is nothing but trouble. It bubbles up, it cracks, it peels... it's a mess.

My wife was actually quite upset that no one at the hospital warned her beforehand that she has to take good care of her soles before going on 5-FU.

Good luck!!

Re: Xeloda (oral) Questions

Eli, thanks for the heads up.  My Dr. and his RN mentioned that hand and foot syndrome was one of the side effects of Xeloda, and to use a good cream.  We have a good cream, so I rubbed it on my feet this morning and put my socks back on.  Using a hand lotion on my hands as well.  So far, no side effects from the new chemo treatment I received yesterday afternoon.  Just up all night from the Dexamethason.

Cindy

Re: Xeloda (oral) Questions

Eli...your wife had reason to be upset and I am sorry to hear that she suffered from peeling and cracking extremities. Patients need to be made aware of possible side effects caused by medications.  Cindy's nurse did what we expect from our health care professionals in that she was informed beforehand in order for her to take necessary precautions to lessen the side effects of the therapy.
The importance of advocating for those we care for has taken on a different meaning in today’s time.  An active participation in understanding medical treatments and the disease is expected of us - not something we are trained to do rather it is something are expected to grow with and you, Eli, are the proof for just that.
All my best wishes,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Xeloda (oral) Questions

Cindy...At night I would slather moisturizing cream on my husband's feet and hands and then protect it with gloves and socks.  It worked well for him.
I also wanted to mention that our Search function can provide you with some additional information regarding your treatment.  Xeloda has many more postings but you will also find some interesting reading in regards to irinotecan.
Sure hope that you can get some rest tonight.  You deserve it.
All my best wishes,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Xeloda (oral) Questions

Marion, just to clarify... nurses talked to us about 5-FU side effects. They gave us an info sheet with all the symptoms and instructions what to do in each case. They even gave us a few samples of the foot cream that hospital recommends.

What they did NOT tell us is to get rid of the thick, hardened foot skin. That's what my wife was upset about.

Anyway, it's all water under the bridge now.

Re: Xeloda (oral) Questions

Thanks again Marion and Eli.  I do tend to have thick hardened skin on my feet, so I have been loading up on the Eucerin cream at bedtime and in the morning again.  Thanks Eli, as my nurse did not mention the thick hardened skin part.  Just the hand and foot syndrome.  I also soften up my hands at the same time!
Every little hint will help!

Cindy

Re: Xeloda (oral) Questions

Although I am not on this chemo I do have sensitive skin.  This cream was recommended to me, called " Udder balm "  Yes it is used by farmers on the udders of cows, to keep those udders moist and able to be milked during the cold winter months.  And the farmers use it also, think of all the nicks and cracks on their hands during the winter months.  As they used it on the cows, they noticed how much better their own hands felt.

It says not to be used on humans, but it works great.  But we have bigger problems to fight than using cow cream on our feet.  My wife goes barefoot all the time and the bottom of her feet were hard, think and felt like medium sandpaper.  Within 2 days of using, we were amazed at the difference.  Just last night she was using some, which made me think of it. 

I get mine locally at a TSC store.  That's Tractor Supply for you city folks.

Grover

Re: Xeloda (oral) Questions

Re: Udder Cream

That's the cream that our hospital recommended. It's not just for cows.... they do make human formula.

http://www.uddercream.com/

Re: Xeloda (oral) Questions

Gee, I wonder what it would do for face wrinkles? Could it be "udderly" fantastic????

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: Xeloda (oral) Questions

Ha, ha, Lainy.....we can always count on you to bring a smile to our faces.

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Xeloda (oral) Questions

Hey Grover, I was at Rural King today and meant to buy some.  My first job out of high school was at Indiana Farm Bureau Co-op, in later years became Countrymark Co-op.  My dream job, I worked there 24.5 years before Land O' Lakes took over and moved it North.  But, anyway, we all used to buy the udder balm and use it on our hands and feet.  There was another product too, called bag balm.  But I seemed to remember that it was a more greasy product.
Sorry for the history lesson!

Re: Xeloda (oral) Questions

Grover - stop talking about mom's crusty, nasty feet on-line, I'm sure she wouldn't appreciate it!!

xoxo, Mom

Re: Xeloda (oral) Questions

Ought oh!  Is Grover in trouble?

Cindy

Re: Xeloda (oral) Questions

not yet, but he better watch it!  Like I tell my kids, Santa is watching!  But that stuff must be good if it's helping mom's feet!

Re: Xeloda (oral) Questions

Hi all,

I am just starting to have some of the hand/foot syndrome. I try to remind myself all day long to put lotion on my hands. It can be hard for me because I am a nurse and I wash my hands alot! Its not so bad yet and hopefully it doesn't get worse. I know I will be able to handle all that comes my way. Thanks all.

Shari

Re: Xeloda (oral) Questions

All:

When Tom was on Xleoda (oral) he never experienced any issues w/hand or foot issues.  When he was on F-FU shortly before he passed away on 11/20/2011 his feet started to show symptoms.  I used just a good skin cream and would put it on his feet and legs every morning and night and it really made a difference for him.

Margaret