My daughter, Lauren, was on Gemzar, Cisplatin, and 5FU for a long time and had a lot of shrinkage. Her doctor took her off Cisplatin a while ago because he didn't want to ruin her kidneys. With the two chemos, things stayed stable. She had a radioembolization therapy called Theraspheres where they shot beads of radiation into the tumors in her liver. It was supposed to kill the tumors targeted. Instead, a new tumor popped up!! So, Lauren just started on Oxaliplatin and Xeloda yesterday. The Oxaliplatin has made her very sensitive to cold. She could not crack her eggs this morning because they were too cold to touch. You are probably wondering why I didn't make her eggs for her. Unless she is really sick in bed, she is so independent, she won't let me do anything for her. One of her hands was numb today and she couln't write very well. Her feet felt really cold on the tile floor in the bathroom. Other than that, she feels ok. No stomach problems so far. They did give her double the amount of Decadron that they usually give her and that is not easy to deal with. We had them drop the dose before because it made her really irritable and she snapped at everyone all the time. They said she needed the full dose with the Oxaliplatin to help if she developed an allergic reaction. Whatever you decide, it is your choice and I am sure you will choose what is right for your husband. All the best to you both.
My beautiful daughter, Lauren Patrice, will live on in my heart forever.
My comments, suggestions, and opinions are based on my experience as a caretaker for my daughter, Lauren and from reading anything I can get my hands on about Cholangiocarcinoma. Please consult a physician for professional guidance.