Mouth sores

bluebird.....I found a few previous discussions regarding thrush:

http://www.cholangiocarcinoma.org/punbb … hp?id=3766

One of the things recommended to us was the line of mouth products called "Biotene".  It comes as toothpaste, mouthwash etc. 
Also rinsing mouth with soda water frequently over the first few days worked as well as salt or baking soda solutions. 

I am sure for others to chime in with their experiences also.
Good luck,
Hugs,
Marion

My wife developed mouth and throat sores when she was on 5-FU. Our oncologist gave us prescription for Sucralfate suspension. The dose was 200mg/ml or 1g/5ml (same thing).

http://www.drugs.com/mtm/sucralfate.html

The brand name in the US is Carafate. Canadian brand name is Sulcrate Suspension Plus.

The great thing about it, you can drink it as well as use it as a mouth wash. Our oncology nurse told us that sores usually extend all the way down to the stomach. In other words, mouth sores are just the tip of the iceberg. When you drink the suspension, it coats the sores in the throat and esophagus.

Zilactin-B is another medication we used. It's a local anesthetic (numbing gel). My wife applied it to the mouth sores before meals, to make eating more comfortable. Zilactin-B is an over the counter medication.

Good luck!

Finally got around to giving you all an update.  The doctors lowered his capecitibine dose and the mouth sores went away (he occasionally gets one but nothing like what he was experiencing before).  They said that all of the trial patients got the sores initially.  The main issue we have now is that twice he had to skip chemo because his platelet count was too low.  He is scheduled for a CT scan on Oct. 5 to see if the trial is working.  The doctor said that if he continues to have low platelets, he may have to discontinue the trial.  Hopefully the trial is working and his platelets will rise.