Topic: Heat shock protein 90

Anyone have any experience or knowledge of this target therapy: HSP90-
heat shock protein 90?  It popped up on my FB page and there's not too much info that I can find on it's significance on cholangiocarcinoma

Anna

Re: Heat shock protein 90

Anna, Gavin just posted a link on this very question today.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: Heat shock protein 90

Hi Anna,

Is this what popped up on your FB page today?

http://www.biomedsearch.com/nih/heat-sh … 55701.html

Have you tried using the search forum function at the top of the page to see what else is here on the site?

Best wishes to you,

Gavin

Any advice or comments I give are based on personal experiences and knowledge and are my opinions only, they are not to be substituted for professional medical advice. Please seek professional advice from a qualified doctor or medical professional.

Re: Heat shock protein 90

The study that Gavin linked was done in a dish.

17-AAG is the name of the drug.  Heat shock protein 90 (HSP90) is the target of the drug.

17-AAG is also known as Tanespimycin. It was tested in a number of clinical trials:

http://clinicaltrials.gov/ct2/results?term=tanespimycin

None of these trials involved cholangiocarcinoma.

This article says that Bristol-Myers (pharma company) has abandoned development of the drug:

http://www.myelomabeacon.com/news/2010/ … nt-halted/