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Anyone have any experience or knowledge of this target therapy: HSP90-heat shock protein 90? It popped up on my FB page and there's not too much info that I can find on it's significance on cholangiocarcinoma
Anna, Gavin just posted a link on this very question today.
Is this what popped up on your FB page today?
http://www.biomedsearch.com/nih/heat-sh … 55701.html
Have you tried using the search forum function at the top of the page to see what else is here on the site?
Best wishes to you,
The study that Gavin linked was done in a dish.
17-AAG is the name of the drug. Heat shock protein 90 (HSP90) is the target of the drug.
17-AAG is also known as Tanespimycin. It was tested in a number of clinical trials:
None of these trials involved cholangiocarcinoma.
This article says that Bristol-Myers (pharma company) has abandoned development of the drug:
http://www.myelomabeacon.com/news/2010/ … nt-halted/
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