Topic: Chemo Agents and Solid Tumor Biomarkers-From Caris Life Sciences

Hi, everyone,

Link=  Agents                 Biomarker     Platform
cisplatin, carboplatin     ERCC1     RT-PCR
                                        BRCA1     RT-PCR
docetaxel, paclitaxel     TLE3     IHC
capecitabine, fluorouracil, pemetrexed     TS (TYMS)     RT-PCR
doxorubicin, liposomal-doxorubicin, epirubicin     TOP2A     RT-PCR
                                                                          Pgp     RT-PCR
irinotecan, topotecan     TOPO1     RT-PCR
gemcitabine                     RRM1     RT-PCR
erlotinib, gefitinib             EGFR     RT-PCR
                                        cMET     IHC, FISH
temozolomide, dacarbazine     MGMT     IHC
nab-paclitaxel                     SPARCm, SPARCp     IHC
abiraterone, bicalutamide, flutamide     AR     IHC
fulvestrant, tamoxifen, toremifene; anastrozole, exemestane, letrozole; megestrol acetate; leuprolide, goserelin     ER     IHC
                                                                PR     IHC
everolimus, temsirolimus     PIK3CA     Sequencing
                                        PTEN     IHC
trastuzumab, lapatinib     HER2     IHC, FISH/CISH
imatinib, sunitinib             cKIT (GIST only)     Sequencing
clinical trials (MEK inhibitors; BRAF inhibitors)     BRAF     Sequencing
clinical trials (MEK inhibitors; BRAF inhibitors)     KRAS     Sequencing
clinical trials (MEK inhibitors; BRAF inhibitors)     NRAS(Thyroid)     Sequencing


God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.