Topic: Chemo & meds

Good afternoon.  I'll keep this short & sweet.  I'm starting to do some research on all the meds my dad is receiving & was curious if anyone has had any experiences with any of them that you could share.  My dad has only had one chemo thus far & it was gemcitabine & cisplatin.  His medicine he takes twice a day to help him eat is magestrol.
My dad still is unable to eat.  Before this monster attacked him, food was his life & now he craves something and then can only take a bite or two at the most.  Thank you for any information.  This site is amazing.

Re: Chemo & meds

Sorry, I forgot a few.  For pain which hasn't helped much is:
Hydrocodone 7.5-3.25 APAP
Patch - fentanyl 2-5mcg HR every 3 days

For nausea: zofron8 mcg hcl

Thanks

Re: Chemo & meds

Hi,
I am sorry,I did not have any experience on those drugs together. I do know its pharmacological use though.
May be other members can help  with their EXPERIENCES.
God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Chemo & meds

Hi MaFoster. I think the loss of appetite goes with the territory and chemo. I used to give Teddy Carnation Instant Breakfast, he loved the vanilla with a banana blended in, this shake takes the place of a full meal and has all the needed nutrients. Also can be used for each meal. I personally am not a believer in pushing food when a patient is not up to it. We recommend 'grazing' during the day instead of full meals. Comfort foods work well too. For pain Fentanyl never worked for Teddy he had Morphine in small doses and as needed later the doses increased. He did have Zofran and it worked quite well. Do you know what pain level Dad is at on a 1 - 10 scale? Never heard of Magestrol but again, I did not give him things to enhance his appetite. Very similiar experience on the wanting to eat but couldn't. I would make him a scrambled egg and toast then he would apologize that I made it and he just couldn't eat it. My bottom line was always pain control and I think when the pain is controlled the rest may follow. Be Strong!

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: Chemo & meds

MaFoster-Hi, I took all the those drugs except the patch. Megace is the generic form of magestrol or vice a versa, it is an appetite stimulant. If I remember correctly it has something to do with medical mariquana, but I was pretty out of it for a long time!!  I really don't remember it making a major difference. I never had any major side effects from any of them. My favorite (if you are suppose to have one) for pain was dilauted, it worked the best for my pain. My doctor also had me on 3 anti-nasuea drugs for nasuea so I always had sonething in my system.
Lots of prayers for your dad-Cathy

Re: Chemo & meds

Hi MaFoster:

Hydrocodone is generic for Vicodin. I was on that after my second surgery when my pain was not as severe. For the first surgery, pain was as issue and I was given hydromorphone, generic for dilauded, and it was effective for me.

During chemoradiation, I was on Zofran and Reglan. Zofran seemed most effective, although I was told I could alternate the two so I could take something a little more often.

I was never on fentanyl or magistrol.

I hope our various experiences help. Obviously everyone responds differently to these drugs, so if something isn't working for your dad, hopefully his physicians can make a change.

Best wishes to you and your father.

Mark

Re: Chemo & meds

Mark-I was wondering if you had any side effects from Reglan, I had major, rapid eye movement, protruding tongue.... I still chew my tongue and haven't had Reglan in 2 years.
Lots of prayers-Cathy

Re: Chemo & meds

Thank you for your responses.  This is still so new & hard to swallow.  It's really happened so fast.  Just a little over 2 months ago dad was on the field passing out all star jerseys to the Texas Rangers, playing in golf tournaments & now to see him so weak & pretty much immobile is beyond devastating.  He started having pain when the blood clots started & being in & out of the hospital during all of that he started getting weak.  Soon thereafter he was diagnosed with this & it seemed he immediately went downhill at a furious pace.  He stays in his recliner, but now his back pain is also getting to be too much, so he tried the bed, but that's not working.  I feel so helpless & it's just so hard.  At one point we even tried to get his doctor to prescribe medicinal marijuana, but they refused.  We were hoping it would increase his appetite & mood at the same time.  I don't live in the same town as my parents to go to the doctor appointments, but I'm going to come up with questions mom could ask the doctor.  They get discouraged because they said she always responds with, "it's the cancer."  Thank you all again.  Your responses are greatly appreciated.

Re: Chemo & meds

Last thing, I think, but my fear is if he doesn't start eating or drinking these shakes, then his body will quit on him.  We need him to fight and conquer this the best he can.

Re: Chemo & meds

Hi mafoster,
I will tell you how my daughter has fared with the drugs she has taken that you listed. The ones I do not talk about were never taken by her. Everyone reacts differently to these drugs, so just letting you know how she reacted to them.

Hydrocodone- She feels it is not very effective alone, but used with Morphine it can be effective for pain. Her pain is not as severe now so she only takes long acting Morphine 2X daily and fast acting Morphine for any breakthrough pain maybe once or twice a week.

Zofran- Gave her migraine like headaches. She takes Compazine and Ativan for nausea and they both work well. Ativan is also for anxiety.

I would let your Dad eat whatever he is hungry for, no matter how much he does or doesn't eat. After Lauren has chemo, she likes bland comfort food like chicken noodle soup, creamed chicken, rice, mashed potatoes, oatmeal. She also has a little trick that if she gets nauseous, she chews spearmint gum and it usually settles her stomach.

I hope this helps. My best to you and your Dad.

-Pam

My beautiful daughter, Lauren Patrice, will live on in my heart forever.

My comments, suggestions, and opinions are based on my experience as a caretaker for my daughter, Lauren and from reading anything I can get my hands on about Cholangiocarcinoma. Please consult a physician for professional guidance.

Re: Chemo & meds

Thank you so much.  I am jotting all of this down to share with my parents.  This is going to sound very stupid, but I'm still learning, but how many different chemo cocktails are used for cholangiocarcinoma & how do the oncologists decide which to use?  I know, that might be a question they need to ask their oncologist, but I thought I'd throw it out there since so many of you amaze me with all your knowledge on this awful cancer. Thanks

Re: Chemo & meds

Hi mafoster,

I had asked Percy for a list of all chemos used for CC and he was kind enough to do it. It is listed under the Forum called Chemotherapy. The topic is Systemic Chemotherapy in General for Cholangiocarcinoma patient by PCL. I hope it helps.

-Pam

My beautiful daughter, Lauren Patrice, will live on in my heart forever.

My comments, suggestions, and opinions are based on my experience as a caretaker for my daughter, Lauren and from reading anything I can get my hands on about Cholangiocarcinoma. Please consult a physician for professional guidance.

Re: Chemo & meds

Hi,
I know you will find info. From this link for some of your questions.
Remember , this is for references only, the doc will decide which one is the best for the patient, but you can ask him/her the regimen in your mind for comparison.

http://www.cholangiocarcinoma.org/punbb … hp?id=7843

God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Chemo & meds

Hi mafoster,

I took compazine and Ativan for nausea and it worked great, zofran did not work for me.
The only pain med that gave me relief was dilaudid.
I still take Ativan for anxiety.
Lisa

This Information Is Not Intended Nor Implied To Be A Substitute For Professional Medical Advice. You Should Always Seek The Advice Of Your Physician Or Other Qualified Health Care Provider

Re: Chemo & meds

Cathy,

Ugh. Your side effects from Reglan soumd awful. I had no such side effects, but I took Reglan only occasionally to supplement Zofran.

Mark.

Re: Chemo & meds

Mark, The funny part is I only understood and knew what was happenning because I saw one of those cheesy lawyer commercials!! I was recovering from second transplant and was pretty drugged and incoherent and knew this things were happenning but didn't know they shouldn't be until I heard one of the those lawyer class action commercial saying "if you have or are..." and it was an OMG moment!! We told my doctors and they took me off it right away!!
Lots of prayers-Cathy

Re: Chemo & meds

Speaking of Reglan:

Reglan has a *major* interaction with Compazine. The two should not be taken together. The side effects can be very serious and irreversible.

You can read about it here:

http://www.drugs.com/drug-interactions/ … consumer=1

Re: Chemo & meds

Eli- I took both together for months, those were pretty much my symptons! I still have tongue issues and it has been almost 2 years!!! Thanks for the   post.
Lots of prayers-Cathy

Re: Chemo & meds

Cathy, I'm sorry to hear that you have these issues.

We had a close call with Reglan and Compazine. My wife got prescription for both from two different doctors. Luckily for us, we fill most prescriptions at the same Costco store. Their computer system caught the conflicting medications. They warned us not to take the two together.

20 (edited by marions Wed, 17 Oct 2012 01:26:59)

Re: Chemo & meds

Eli and Cathy....this is so important for others to know.  I am wondering whether it would be best to have the above info under a special heading in the "Side Effect" section also. 
Under normal circumstances Rick would be able to accommodate us however; at the moment we (the board members) are working through some major issues, all under severe time constraint.
We could add it to Rick's "to do" list however, I am concerned that someone else may experience what you Cathy, have gone through and what you Eli, have been able to prevent with Marina. 
What do you think? 
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Chemo & meds

Marion,

Most internet discussion forums use "sticky threads" or "sticky topics" to highlight the most important information.

Sticky topics are topics that always show up at the top of their sections. An administrator or a moderator has the ability to stick a topic to keep it at the top.

In this case, we need a sticky topic in the Side Effects section, called something along the lines:

"Major Interactions Between Commonly Prescribed CC Drugs"

All important information should be in the first post of the topic, to make it easy to find. As new information becomes available, it should be added to the first post (by editing it).

Many internet forums close sticky topics to member discussions. In other words, only moderators have the ability to add/edit information in a sticky topic. The goal is to keep the sticky topics concise, clean, and easy to comprehend.

Re: Chemo & meds

Sounds perfect, Eli.  Your computer knowledge is beyond my comprehension. 
Thanks again,
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER