Topic: Yttrium-90 Radioembolization

Yttrium-90 Radioembolization for Unresectable Standard-chemorefractory Intrahepatic Cholangiocarcinoma: Survival, Efficacy, and Safety Study.

http://www.ncbi.nlm.nih.gov/pubmed/22956045

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Yttrium-90 Radioembolization

Thanks for that Marion.

Any advice or comments I give are based on personal experiences and knowledge and are my opinions only, they are not to be substituted for professional medical advice. Please seek professional advice from a qualified doctor or medical professional.

3 (edited by PCL1029 Mon, 17 Sep 2012 10:02:51)

Re: Yttrium-90 Radioembolization

Hi,

We had three patients on this board who had radioembo during the last 6-8 months; and all of them had been passed away.
I ,at this point, will reserve my opinion on this interventional radiological treatment until I can learn more about it.
I knew one of them may be related to the leakage of Y90 into the lungsafter the radioembo.
The other one  may be because of his pre-existed heart condition (pacemaker) and lung nodule(which had been wedgely removed), but his condition is stable(after liver resection  and no CCA left as far as the last CT 6month prior(?)shows);he was on 6month of adjuvant chemotherapy of Gemzar after resection.
The third one I still don't know for sure; He was actually had a 61% shrinkage of the tumors(one big one and a lot of the small ones.and he just want to to enjoy life more,he was 43 at that time?) ;but I suspected it was the side effects  of panitumumab being mentioned quite often is pneumonitis ,pulmonary fibrosis and cough that causing him problems even after stopping the regimen for a month or so before the radioembo was performed.,but this is just my guess.
But 2 of them were on chemotherapy (GEMOX)+ targeted agents (EGFR inhibitor) before they were administered the Y-90 radioembo treatment. And it seems to support the observation that patients received cetuximab and the like before Y 90 treatment will have a shorter overal survival.
Two of them had stopped chemotherapy 10 days to 2weeks befor radiochemo which was recommended or ok by their doctors ; well short of the 4weeks recommended by others .

God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Yttrium-90 Radioembolization

Hi everyone! I just want to share the good news that my Mom received last Wednesday. 
My Mom had 2  Y-90 treatments, one in July and the other one in September.  Based on her latest CT Scan, her IR Doctor is very pleased with the results. According to him, more than 90% of her large tumor is dead!
Her next Oncology appointment will be in November. Maybe another round of chemo???

GOD is good.

Re: Yttrium-90 Radioembolization

Hi Percy. Just wanted to remind you that my Lauren had Y-90 in May and the verdict is still out on how much it helped. She had it on the side of her liver that had some small tumors in hopes to get rid of them all so she could have a resection of her large tumor. She had a lot of chest pain after the procedure especially when she burped, but it eventually went away. She did develop a 4 cm. lesion after the procedure on the side that was treated and to this day they can't tell if it is a tumor or a dead spot from the Y-90, thus the not knowing if it worked or not. She does only have 2 spots on that side of her liver instead of 5, so we are optimistic that it worked. Her large tumor is over 50% dead from chemo, so she is in a better place than she started out.

My beautiful daughter, Lauren Patrice, will live on in my heart forever.

My comments, suggestions, and opinions are based on my experience as a caretaker for my daughter, Lauren and from reading anything I can get my hands on about Cholangiocarcinoma. Please consult a physician for professional guidance.

Re: Yttrium-90 Radioembolization

Dear lbutiong, I LOVE waking up to your kind of post! YIPPEE for your Mom! I have everything crossed for a GREAT appointment in November. May the good news continue!

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: Yttrium-90 Radioembolization

Hi,
This is the doctor who talked about the Y90 in plain English that layman can understand. He is considered one of  the top doctor in this field around the world,therefore experiences count a lot.
If you read what he said carefully, you will understand how he feels about this procedure when things was not going his way  . He is not just want to perform the Y 90  procedure only; he is chasing and trying to improve  the utility of this procedure for better results for liver and other tumors. And that is the difference of hearts among medical professionals.

http://www.io.northwestern.edu/patient- … -illinois/

God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Yttrium-90 Radioembolization

My 86 year old mother is considering radioembolization for a 5 cm liver tumor, HCC, that has invaded into her portal vein, but does not appear to have spread further.  Until a few weeks ago, she was an unusually active 86 year old, but in the last few weeks, she has grown weaker.  Thus we are leaning towards radioembolization (at Stanford, Dr. Sze and Louie) ASAP.

I have seen information that makes it clear that we can expect some 'side effects' in the first days or perhaps 1-2 weeks afterwards - fatigue, pain, nausea.  The notion that treatment is followed by short-term side effects does not worry my mother.

However, we have not seen literature on what we might expect with regard to undesired side effects in the next, say, 2-3 months.  I only know one person who had this treatment, and she had NO side effects.  But is that common?  I realize that we might not see clear positive effects in the first 2-3 months, but will we also likely see little/no negative side effects?  If you have relevant experience or information on positive or negative changes following radioembolization, I'd love to hear your thoughts.

Re: Yttrium-90 Radioembolization

Hello Daviscalifornia, wlecome to the best little club in the world that no one really
wants to join! I am sorry about your mother and while I cannot help with RE I know that others will come along with some answers. I do have a suggestion though that you repost under Introductions so that this post does not get lost in this different thread. Wishing her the very best and for yourself, please be strong! Also please keep us updated on her as we truly care.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

10 (edited by PCL1029 Mon, 22 Oct 2012 17:46:32)

Re: Yttrium-90 Radioembolization

Hi,
About side effects of radioembo, please see below.

http://www.cholangiocarcinoma.org/punbb … hp?id=8626

But please be aware that these patients also have been  on chemotherapy at the same time when radioembo were performed.


God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Yttrium-90 Radioembolization

Hi Davis,

My Mom had Y-90 treatments last July and September. No significant side effects except for fatigue. So far, so good...

I hope your Mom feels better.