Topic: Has anyone been on this regimen?

My dad was diagnosed in early September with Stage IIIA intrahepatic CCA.  He completed two cycles (four doses) of gem/cis; however, his CT scan yesterday showed significant GROWTH in the four largest tumors.  The consulting oncologist at the medical university recommended 5-FU with Leucovorin and Camptosar.  Has anyone experienced this specific regimen?  If so, what results did you have and what side effects did you experience?

Re: Has anyone been on this regimen?

Dear Leah, welcome to our remarkable family but sorry you had to find us. I can't help with Chemo but wanted to say I know someone will be along to help. In the meantime a the top of the page is a Search button. If you just type in the word of what you are looking for other posts will come up on that subect. Please also keep in mind that we always recommend 2nd and 3rd opinions. Wishing you the best of luck.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: Has anyone been on this regimen?

Hi Leah,

I wanted to welcome you to this site. I am sorry to hear about your Dad. The only one of the three my daughter has been on was 5-FU. Hers was given over 48 hours. She wore a little fanny pack that held a pump and her chemo. I have heard of Leucovorin, but don't know much about it. I had never heard of Camptosar, so I looked it up and it is also called Irinotecan, which I know some people on this site are on. I'm sure others that are familiar with this chemo regime will help you out. With the 5-FU, Lauren had no trouble with it. I learned from a nurse at the hospital how to disconnect it and flush my daughter's port. It was very easy. That way we didn't have to make a special trip to the hospital. That would not have been practical since we are 3 1/2 hours away!! I wish your Dad all the best with his new plan. Please keep us informed as to how he is doing.

-Pam

My beautiful daughter, Lauren Patrice, will live on in my heart forever.

My comments, suggestions, and opinions are based on my experience as a caretaker for my daughter, Lauren and from reading anything I can get my hands on about Cholangiocarcinoma. Please consult a physician for professional guidance.

4 (edited by PCL1029 Thu, 15 Nov 2012 19:21:27)

Re: Has anyone been on this regimen?

Hi,

http://www.cholangiocarcinoma.org/punbb … 198#p57198

http://www.cholangiocarcinoma.org/punbb … 833#p58833

Www.chemoregimen.com



God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Has anyone been on this regimen?

Hi Leah.  I'm a new member too.  My husband had a resection a year ago today but his CC has recurred as it so often does.  He just started FOLFIRINOX which is made up of the three drugs you mentioned plus Oxaliplatin.   Leucovorin is just a type of folic acid that makes the other drugs more effective and it has few side effects.  The doctor said the other drugs all have side effects and that some people have particular trouble tolerating the Irinotecan (Camptostar).  However, the regimen has been shown to be more effective than the alternatives in pancreatic cancer patients so there is hope it may also be more effective in treating cholangiocarcinoma.  We were expecting some major side effects but, other than a little nausea the first day, my husband has not had any side effects so far.  All my best to your dad.

Re: Has anyone been on this regimen?

Enclosed is a link to a study for the above regimen:
http://www.asco.org/ASCOv2/Meetings/Ann … ocarcinoma

Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Has anyone been on this regimen?

Thanks everyone.  We meet with our primary oncologist Monday to discuss a new treatment plan.  Not sure if we'll got with FOLFIRI as recommended or if he will choose to go a different route with FOLFOX, FOLRIFINOX, or something completely different.  For now, we're thankful for the good days we're enjoying between chemo cycles.

Re: Has anyone been on this regimen?

Dear Leah, you have caught on fast! Enjoy the good days to the MAX and good luck on Monday! I know you will give us the update.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.