I wanted to welcome you to this site. I am sorry to hear about your sister. My daughter, age 26, has CC as well. While I don't know about the cancer center your sister is being treated at, I do know about our experiences with Gem/Cis. My daughter was on that for her first chemo along with another chemo called 5-FU. She tolerated all the chemos well. Cisplatin was the hardest on her. Platelet levels tend to dip when on it and they need to be 100,000 or more to receive it. She felt pretty crummy the first few days after chemo then came back around. Make sure they give your sister iv nausea meds before chemo. Lauren always gets a drug called Aloxi, but there are others. Also make sure she has nausea meds for home. We have found Compazine to work the best for Lauren, but many people also use Zofran. Zofran gives Lauren bad headaches. Lauren also lost her hair on this chemo combo, but it has since grown back. She has just been put back on Gemzar so she might lose it again, but if that's the worst of her worries we'll take it! Lauren had the best results with that chemo combination, but sadly cancer becomes smart and resistant and another chemo must be tried after time. I am hoping everything goes well for your sister. Please keep us updated. All the best to you both.
Hoping for a miracle for my daughter, Lauren.
My comments, suggestions, and opinions are based on my experience as a caretaker for my daughter, Lauren and from reading anything I can get my hands on about Cholangiocarcinoma. Please consult a physician for professional guidance.