Cardio toxicity of 5FU include angina,arrhythmias including,Ventricular tachycardia,cardiogenic shock,chest pain(unspecified),coronary vassos plasm,myocardial infarction,palpitations,electrocardiographic changes and sudden death.
Patient who have cardiac problems should mention it to the doctor before starting 5FU or capecitabine. And adequate hydration is helpful.
Beta-blockers such as Lopressor; calcium channel blockers such as Diltiazem and nitrates such as nitroglycerin tablet or the patch will help to relieve the chest pain.
Upon such findings, as a patient on Xeloda for almost a year, once again, I will tap into my resources to see what they can suggest to me.
Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.