1 (edited by marions Sun, 27 Jan 2013 20:12:32)

Topic: GI ASCO, 2013, San Francisco, your donations at work

The Cholangiocarcinoma Foundation in conjunction with the Conquer Cancer Foundation (ASCO) provided crucial funding for Cholangiocarcinoma Research. In 2011 the Cholangiocarcinoma Foundation funded a Young Investigator Grant in the amount of 50 thousand Dollars to Dr. Flavio Rocha, MD, of Virginia Mason Medical Center for his research project “CEACAM6 as biologic marker and prognostic of biliary malignancy”.   

With the support of his research team, Dr. Rocha has been able to determine that CEACAM6 is a protein that is indeed present in cholangiocarcinoma, and that in a certain type of cholangiocarcinoma that arises inside the liver, the presence of this protein in the tumor is a marker of more aggressive disease.  Dr. Rocha’s team has also identified CEACAM6 in the bile of patients whose cholangiocarcinoma had been surgically removed, and they are working to compare levels of the protein in the bile of patients without cancer to determine if it can be used as a marker of disease presence or response to treatment.

“If these markers can be shown to pinpoint cancerous tissues and distinguish them from normal bile ducts, then they can be used to design better imaging tools or therapeutics,” Dr. Rocha said. 

The Cholangiocarcinoma Foundation contributed 60 thousand Dollars to the Long Term International Fellowship grant received by Suebpong Tanasanvimon, MD, Of King Chualongkorn Memorial Hospital, Thailand.  The combined grant of 110 thousand Dollars (Conquer Cancer foundation and Cholangiocarcinoma Foundation) enabled him to pursue a research project focused on cholanciocarcinoma at the University of Texas MD Anderson Cancer Center under the mentorship of Milind Javle, MD.  In some parts of the world, a parasite called a liver fluke can infect the bile ducts and cause cancer.  Dr. Tanasanvimon, with the support of the funding, sought to determine if the miRNA expression profile of cholangiocarcinoma associated liver fluke infection differed significantly from the miRNA expression profile of spontaneous cholangiocarcinoma. 

The results of his study demonstrate that the microRNA expression profiles are different between these two groups, confirming that THEY ARE TWO SEPARATE ENTITIES. 

Dr. Tanasanvimon plans to use the knowledge and experience he gained at MD Anderson Cancer Center to conduct pioneering cholangiocarcinoma research in Thailand.

Dr. Rocha received the Young Investigator Award for his project; Dr. Tanasanvimon received the Long-term International Fellowship (LIFe) Award. 

Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: GI ASCO, 2013, San Francisco, your donations at work

Thanks so much, Marion!!

Re: GI ASCO, 2013, San Francisco, your donations at work

You are welcome.  Both physicians will present a follow-up webconference on our site within the next few weeks. Will keep you and everyone posted. 
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: GI ASCO, 2013, San Francisco, your donations at work

Hi Marion,

I know I have told you this before, but you are a rock star!!!! Thank you so much for your tireless dedication. Well, maybe not tireless, because I know you must be exhausted. So, thank you for all you do to help fight this horrible disease. We sure do appreciate it! Love you!!!

-Pam

My beautiful daughter, Lauren Patrice, will live on in my heart forever.

My comments, suggestions, and opinions are based on my experience as a caretaker for my daughter, Lauren and from reading anything I can get my hands on about Cholangiocarcinoma. Please consult a physician for professional guidance.

Re: GI ASCO, 2013, San Francisco, your donations at work

This is great. Love seeing the research for cholangiocarcinoma. Thanks for all you do Marion.

Re: GI ASCO, 2013, San Francisco, your donations at work

Thank you to each and everyone involved with our foundation; may it be behind the scene or right up front; our members, moderators, and those who graciously donate to our cause.
Hugs to all of you wonderful people,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER