• Gavin
  • Gavin
  • Moderator
  • Offline
  • From: Scotland - Dundee
  • Registered: Tue, 23 Sep 2008
  • Posts: 4,831

Topic: Perineural Invasion and Preoperative Serum CA19-9 as Predictors of Sur

Perineural Invasion and Preoperative Serum CA19-9 as Predictors of Survival in Biliary Tract Cancer

http://ar.iiarjournals.org/content/33/2/583.abstract

  • From: monmouth junction, nj
  • Registered: Sat, 05 May 2012
  • Posts: 50

Re: Perineural Invasion and Preoperative Serum CA19-9 as Predictors of Sur

hi gavin! i can't access this journal article (some i can, since i'm affiliated with an academic institution--my institution doesn't subscribe to this one.) can you tell me if PNI WITHOUT elevated pre-op CA19-9 is prognostically significant? thanks!

  • eli
  • eli
  • Legend
  • Offline
  • From: Ottawa, Ontario, Canada
  • Registered: Tue, 08 Nov 2011
  • Posts: 561

Re: Perineural Invasion and Preoperative Serum CA19-9 as Predictors of Sur

Hi Audrey,

I can't access the full article as I don't have any journal subscriptions. Based on reading the abstract alone, I think the answer to your question is Yes.

I read the same thing before in a few other studies. PNI seems to be a negative prognostic factor, in and by itself. Those studies didn't examine pre-op CA19-9.

Eli

4 Reply by marions (edited by marions Sat, 09 Feb 2013 02:45:14)

  • Registered: Fri, 12 May 2006
  • Posts: 8,157

Re: Perineural Invasion and Preoperative Serum CA19-9 as Predictors of Sur

Found this related study:
http://link.springer.com/article/10.100 … -z?LI=true

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER