Topic: Nerium Oleander Extract

This product is intended solely as a food supplement to enhance general health, and is not intended to diagnose, treat, cure, or prevent any disease. Nothing listed here should be considered as medical advice for dealing with a given problem. You should consult your health care professional for individual guidance on specific health problems.

Sutherlandia OPC extract is made up of a patented and proprietary mixture of two herbal extracts which, in combination, have powerful immuno-modulatory and cytotoxic effects.

 
Topics in this section:
Sutherlandia Frutescens    Sutherlandia Research
Nerium Oleander    Toxicity Studies
Conclusion    Possible Adverse Effects
Usage     
 
Sutherlandia Frutescens
Sutherlandia Frutescens, or “cancer bush” as it is known by the indigenous people of Southern Africa, has been used for centuries to treat a variety of ailments. Its popularity has been publicly acknowledged by its appearance on a South African postage stamp.
    It has powerful immune boosting properties and has been classified as an adaptogen. (An adaptogen is an herbal substance or “tonic” that helps the body to adapt to environmental and internal stress by changing body metabolism.)
Sutherlandia is a flowering shrub of the pea family that grows up to 1.2m high and is found in its natural state only in the drier areas of the Western and Northern Cape provinces of Southern Africa

The use of medicinal preparations from the leaves has been recorded for the following conditions:
Anxiety    Arthritis
Asthma    Backache
Blood Cleansing    Cancer
Chronic Fatigue Syndrome    Depression
Diabetes (type 2)    Edema
Fever    Gastric Ailments
Heartburn    Hot Flushes
Hypertension    Influenza
ME    Peptic Ulcer
Rheumatism    Rheumatoid Arthritis
Viral Hepatitis    Wasting from cancer, TB and AIDS
 
It has also been used as an appetite stimulant for people wasted by disease though it does not stimulate the appetite of healthy people.
Research has shown that the active ingredients in Sutherlandia consist of a mixture of L-canavanine (an amino acid with documented anti-cancer, antiviral, anti-fungal and anti-bacterial action), pinitol (used in clinical settings to treat the wasting syndrome associated with cancer, TB and AIDS), gamma-aminobutyric acid (GABA - an inhibitory neurotransmitter that produces a sense of well-being), L-arginine (an antiviral agent), saponins and gamma sitosterol. Although the exact mechanism by which improvement of ailments is brought about is still relatively unknown, studies have shown the Sutherlandia could help diabetics by inhibiting inflammation and by its improvement of hyperglycemia. It has also been shown that the herb can positively affect the secretory function of the pancreas.

Apart from the papers mentioned below, a number of promising projects are presently being undertaken by various research institutions to test the efficacy of Sutherlandia Frutescens. It is a medical herb with a long history and well-documented research.

 
Sutherlandia Research
Chinkwo KA. - Sutherlandia frutescens extracts can induce apoptosis in cultured carcinoma cells. J Ethnopharmacol. 2005 Apr 8;98(1-2):163-70.
Fernandes AC, Cromarty AD, Albrecht C, van Rensburg CE. - The antioxidant potential of Sutherlandia frutescens. J Ethnopharmacol. 2004 Nov;95(1):1-5.
Harnett SM, Oosthuizen V, van de Venter M.- Anti-HIV activities of organic and aqueous extracts of Sutherlandia frutescens and Lobostemontrigonus. J Ethnopharmacol. 2005 Jan 4;96(1-2):113-9.
Ojewole JA. - Analgesic, antiinflammatory and hypoglycemic effects of Sutherlandia frutescens R. BR. (variety Incana E. MEY.) [Fabaceae] shoot aqueous extract. Methods Find Exp Clin Pharmacol. 2004 Jul-Aug;26(6): 409-16
Tai J, Cheung S, Chan E, Hasman D. - In vitro culture studies of Sutherlandia frutescens on human tumor cell lines. J Ethnopharmacol. 2004 Jul;93(1):9-19.
 
Nerium Oleander
    Oleander has been used for medical purposes for more than 2000 years. In biblical times it was known as the “desert rose”.
In Turkey, it has been used as a folk remedy for centuries.
During the 1960s, a Turkish doctor, Huseyin Ozel, saw that people using the remedy were mostly free of cancer and other serious diseases. He knew about the poisonous nature of the plant but soon discovered how to prepare the extract used as folk medicine. As head of the surgical department of the Mugla State Hospital in Turkey, he started experimenting with the extract and subsequently successfully used it as a treatment for cancer for more than 35 years. At the request of his son, Dr Ozel patented an aqueous extract of Nerium Oleander as ANVIRZEL. (US Patent #5,135,745) The Nerium Oleander extract used in the Sutherlandia OPC proprietary herbal mix is similar to the ANVIRZEL extract and the following excerpt is taken from the description of ANVIRZEL on the Internet: (the oral form of ANVIRZEL and Oleander Extract are the same)
Extensive laboratory and clinical experience indicate both cytotoxic and immunological activities for the drug. In developing a protocol for clinical trials, M.D. Anderson Cancer Center states, "It is thought that the polysaccharides present in Oleander Extract are capable of activating the immune cells, which in turn can recognize the epitopes present on the cancer cell surfaces, thereby enhancing the efficacy of the immune response. It is believed that the cytotoxic action present in the extract may be essential for synergistic activities. It is believed that the cytotoxic action both arrests tumor growth and prevents cancer cell reproduction as well as having and/or producing a Tumor Necrosis Factorlike activity. Research has proved conclusively that Oleander extract is active on dual pathways at the cellular level to both inhibit the growth of tumor cells (through the antiangiogenesis activity of the oleandrin) and to promote apoptosis of the tumor cells.

Extensive in vitro research has been conducted by Dr. Robert Newman, Chief of Pharmacology, M.D. Anderson Cancer Center (MDACC), Houston, Texas. Dr. Newman has tested Oleander Extract against a broad spectrum of human malignant cell lines, and has demonstrated that Oleander Extract has a high order of efficacy.

In addition to the research being conducted by M.D. Anderson Cancer Center, concurrent research is being conducted by Dr. Wendell Winters, a noted immunologist with the University of Texas Health Science Center in San Antonio,Texas. Dr. Winter's work has confirmed that Oleander Extract has been "shown to stimulate the immune system by stimulation of the function and capability of specific subsets of mononuclear cells." In addition, Dr. Winters' research has shown that Oleander Extract specifically stimulates T and B lymphocytes, the cell-mediated and the humoral mediated immune systems.

In April 2000, a USFDA approved study entitled "Phase I Study of ANVIRZEL in Patients with Advanced Solid Tumors" was commenced under the direction of Ronald Buckowski, M.D. at Cleveland Clinic in Cleveland, Ohio.

Because of its strong cytotoxic effect in combination with an equally strong immunomodulatory effect, Oleander Extract is indicated as a therapy, both primary and adjuvant, for cell proliferative disease (cancer), certain viral disease, and autoimmune/inflammatory disease. Clinical application of Oleander Extract in the United States, Ireland, and Honduras has demonstrated efficacy against various neoplastic disease, hepatic disease such as Hepatitis C, late and early stage HIV/AIDS, as well as autoimmune/inflammatory disease such as rheumatoid arthritis and psoriasis. The results have been determined both by the clinical practitioner and independent laboratory analysis using PET, CT scan, MRI, and hematological screening.

Using Oleander Extract Therapy, international clinicians have been treating patients suffering from the above referenced disorders on a compassionate use basis since 1997. Many of these patients were previously diagnosed as terminal. These clinicians have experienced a very high level of success with disease stabilization, partial remission, and complete remission, almost always accompanied by a very marked improvement in the patients' quality of life.

Dr. Anibal Villatoro of Tegucigalpa, Honduras, Former Executive Director of the Honduran Institute of Social Security (administrator of the public health system) has since January of 1999 been conducting a compassionate use trial with Oleander Extract for HIV (SIDA) patients in Tegucigalpa. His early results indicate a strong level of response to Oleander Extract therapy with a feeling of homeostasis (feeling of well being) and an improved quality of life, as well as significant improvement in their immune systems. (Reports that slipped out in late 1999 showed that Oleander Extract reversed AIDS, no matter what the phase of the disease, arthritis, psoriasis, hepatitis C, and even diabetes in some cases. Initially, Oleander Extract was thought to work only on cancers found early, however, very positive results have been found in people given just weeks to live. To top this all off, Oleander Extract seems to be the first cancer remedy to show positive results for leiomyosarcoma, probably the deadliest of cancers. Oleander extract also crosses the blood-brain barrier (like Poly-MVA) and gives hope to people with brain tumors.)

The "Common Thread" running through almost all of the clinical records of the patient population using Oleander Extract on a compassionate use basis has been the marked improvement in the "quality of life" of those patients. This includes, but is not limited to, homeostasis, marked improvement in pain management with elimination of or marked reduction in use of analgesics, positive response to antibiotics, increased appetite with concomitant weight gain, and increase in energy with reduction of fatigue.

 
Toxicity Studies
Sutherlandia Frutescens
There have been no reported adverse effects of the herb. A safety study, funded by the South African Medical Council, was conducted over a period of 3 months using 16 vervet monkeys. Behaviour of the animals was monitored and blood tests as well as various physiological evaluations were normal. No toxicity was found even at large dosages.
Nerium Oleander
A toxicity study was performed by Southern Research Institute, Birmingham, AL, on 28 beagle dogs, and the study states, "No clinical signs of toxicity were noted in any of the dogs in this study..." Another lethality assessment of ANVIRZELTM in a murine (laboratory mouse) population was conducted by Southwest Research Institute, San Antonio, TX., and the study states, "On the day of NOI (Nerium Oleander Extract Injectible) administration and over a subsequent 14 day post dose period, none of the treated animals showed any pathological signs or ill effect of the injections as assessed by daily morbidity and mortality observations."

No reports of toxicity have been received from clinicians supervising patients experiencing Oleander Extract Therapy.

 
Conclusion
The herbal components that make up the Sutherlandia OPC mixture are individually both effective traditional remedies. The proprietary mix combines their known effects and the following people may obtain beneficial results from the product:
People with an impaired or suppressed immune system from any cause
People with a high occurrence of infectious diseases, including colds and flu
People with allergies or skin conditions, including skin cancer
People with various types of cancer
People undergoing chemotherapy and/or radiation
People over the age of 40 when the immune system starts to slow down due to the natural aging process
People affected by extra free radical production from external sources such as UV radiation, electromagnetic fields, poor nutritional habits and toxic chemicals
People with chronic diseases such as diabetes, chronic inflammation and chronic fatigue
Professional and amateur athletes, or anyone who works out intensively
People under severe physical or emotional stress
People with arteriosclerosis. Sutherlandia OPC helps draw extra cholesterol from the blood, thus preventing further plaque formation on the arterial walls
People with autoimmune diseases. Sutherlandia OPC helps the system to maintain homeostasis
People with HIV/AIDS
 
Possible Adverse Effects
Possible side effects from this herbal mix when used as a dietary supplement may be slight nausea and vomiting, diarrhea, pruritus, pain at a tumour site, tachycardia and arrhythmias. Because of its blood-thinning properties, people on medical blood-thinning preparations should consult their doctors before using the OPC. People on heart-active drugs, such as digoxin (Lanoxin®) or anti-arrhythmics should also speak to their doctors before using the mixture. No other drug interactions have been reported. Pregnant women should preferably not use the mixture due to its anti-angiogenesis effect. Other short term detoxification symptoms like a slight rash, runny nose, pimples, slightly painful joints, etc, may be experienced. The Sutherlandia in the mixture may cause a slight dryness in the mouth.
 
Usage
5ml (1 teaspoon) or 1 capsule three times per day with meals
(total of 15ml or 3 capsules per day).
The capsules contain the identical active ingredients as the liquid.

Re: Nerium Oleander Extract

Case Report: Cholangiocarcinoma
A white female patient born in Jan. 25, 1962 experienced abdominal pain and weight loss. Obstructive jaundice then occurred. ERCP (endoscopic retrograde cholangiopancreatography) and CAT scan were performed a revealed a significant stricture of the common right and left hepatic ducts. A stent was implanted and the patient underwent surgery and was found to have a small cicatrising mass at the hilum which involved the port vein posterially with adjacent metastatic lymph nodes. Biopsies confirmed the presence of an infiltrating carcinoma consistent with primary carcinoma of the bile duct. A segment III bypass was then performed. The patient's jaundice settled but the patient was discharged from the hospital when it was determined that chemotheraphy and/or radiotheraphy were not likely to be of any benefit to her.

By the time that the patient presented to a hospice (approximately 3 months after onset of the original symptoms), she had lost approximately 42 pounds and was in very poor medical condition. The patient started NOE treatment in an initial regimen comprising a daily I.M. injection dosage of 0.3 cc which was increased to 0.5 cc after one week and maintained.

The patient's general medical condition improved gradually. After approximately 3 months of treatment, the patient had gained approximately 28 pounds in weight and a follow-up CAT scan revealed no tumoral mass. An ERCP was performed approximately two months later to remove the stent. The ERCP also confirmed the absence of a tumoral mass.

The patient was then placed on a maintenance regimen comprising sublingual adminstration of NOE extract 3×0.3 cc every day.

Re: Nerium Oleander Extract

I was diagnosed with Stage IV Bile Duct (Cholangiocarcinoma) in Jan 2012. I had Chemo (Gemzar, Oxaliplatin) for six months. This combination of chemos decreased the tumor marker in the beginning, but did nor work after that. My oncologist put me on Xeloda in Aug 2012. It worked for a few months and tumor marker went down, but then it stopped having any positive effect, too. The tumor kept on growing. I had radiation to one part of of tumor for about 25 days. It shrunk that part of the tumor but cancer spread to a couple of ribs and some other parts of liver. Now I am looking for an effective Clinical Trial for this disease.
Will Nerium Oleander Extract (NOE) will help me? Looking for any effective treatment.

Thanks

Bill Lawrence
Germantown, Maryland, USA

4 (edited by PCL1029 Tue, 19 Mar 2013 11:31:09)

Re: Nerium Oleander Extract

Hi,
This subject matter should belong to CAM ( complimentary and alternative  medicine ). It is not an FDA approval medication and as  Narinder Singh said it is classified as dietary supplement only and their efficacy is not evidance-based like FDA approval drug. Therefore buyer and users be aware.
God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Nerium Oleander Extract

I agree with Percy.  Complimentary and alternative medicines do not undergo the rigorous testing's required for FDA approval.  Hence case studies such as the one presented above, need to be approached with caution. 
This link offers an easy understanding of Clinical Research Studies - it sets the gold standard for drug approval and assures patient protection in all aspects of each individual trial.  http://www.cancer.net/all-about-cancer/ … cal-trials

The Cholangiocarcinoma Foundation has a direct feed to clinicaltrials.gov approved research studies:
http://www.cholangiocarcinoma.org/clinicaltrials.htm

Additionally, TrialCheck offers individualized information
https://www.eviticlinicaltrials.com/services/

It is of most importance that you discuss with your physician the possibility of entering a clinical trial, as he/she will help you guide to the correct study.
Bill, often we compare Cholangiocarcinoma to that of a chronic disease by putting out the fires as they arise.  I am hoping that the metastases to the spine can be controlled with radiation and that you will find for one or the other medications best suited for you. Fingers are crossed and tons of positive thoughts are heading your way. Please stay in touch.
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Nerium Oleander Extract

I know this is an old cliche but, "If it sounds too good to be true, it probably is not true". Otherwise wouldn't most Doctors be recommending it? ANd a reminder, NEVER take anything without your ONC approval first!

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: Nerium Oleander Extract

My advice is to do extensive research in whatever might interest you in aiding your physical and mental health. In my fathers case he was given 6 months to live and we were blessed by having him for 7 years post diagnosis and that was without surgical or pharmaceutical intervention. I'm 35 years old now and a father of two and in my short time i think i may have learned a thing or two. Things in this world are not always what they seem. therefore when one suggests "the rigorous testing's required for FDA approval" i'm sure there are many arguments for and against what the FDA does and how Big Pharma do there "testing". No one person or peaople have the answer to everything in this world, so to me when one is steadfast in their opinion over something that may or not be true seems irrational.  The philosophy that helped my father and my family during our difficult time is that god has given us everything we might need. I praise the doctors and care staff around my father as they all played thier parts to the fullest, in part i believe because we were informed consumers, this website was crucial. I pray for all of you, that God gives us all strength to continue.

8 (edited by marions Mon, 25 Mar 2013 12:04:38)

Re: Nerium Oleander Extract

Narinder…..Much of what you say I agree with.  Pharmaceutical companies are in the business of making money, but I don’t see much difference in the mass marketing of herbal supplements either. The only and crucial difference lays in the oversight that allows these drugs/herbs to be marketed.  Having said that, a  large number of modern drugs owe their origin to botanical remedies.  In fact, the World Health Organization estimates that approximately 25% of modern drugs used in the United States have been derived from plants.  Personally, given my European background, I very much prefer using natural ingredients in food for consumption and herbs for numerous ailments to that of pharmaceutical drugs.  However; once a disease or ailment becomes acute I believe that we have to resort to treatments widely researched and clinically proven.  The regulatory process is pretty stringent at the FDA, requiring drugs to undergo rigid testing before entering the market.  And, within this lays the crux of the matter – supplements/herbals do not undergo these large scale studies. Hence consumers don’t have the benefit of protection needed to assure that the herbs/supplements offered truly are beneficial and not cause harm to the person.  We could argue that many drugs legally distributed also cause harm, and that it correct, but then again we have a bit more oversight over said drugs.  There is no reason to believe that some of the herbs used for centuries could not be a effective as some of the drugs legally sold, but given the fact that natural products such as these can’t be patented, companies are not interested in conducting clinical trials to assure the safety and efficacy of these herbs and supplements.  And, unfortunately, it takes millions and more to conduct these trials and these monies are provided by Industry only.
Is the FDA foolproof – absolutely, it is not in fact, it is undergoing much scrutinity in numerous aeas including the slow process of delaying bringing life saving drugs to the patient community.   
Clinical Trials are conducted in phases I, II, III and IV with the later being ongoing and indefinite.  Hence we often see a drug recalled (years later) due to the fact that even though it proved effective in the early years, the long term use showed to be either not beneficial or even harmful to the consumer.  By no means is it a perfect world, but when confronted with a serious disease, we only so much to go by and that is what has been proven clinically.  Or, we make decisions based on our own research and work with those experts supporting our ideology in order to combat a disease little understood and potentially devastating to the patient.
Your father benefitted greatly from the approach taken by you and your family and possibly you have shared with us a winning combination of how to achieve long term success with this devastating cancer, but we simply don’t know how it worked and whether it works for someone else also. 
For the present I relish the fact that you have done a superb job in providing the best of care for your dear father and that is something to cherish forever.  He was a wonderful man to have raised such a fine son.
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

9 (edited by PCL1029 Sat, 30 Mar 2013 08:31:32)

Re: Nerium Oleander Extract

Hi, Singh,
We both know how valuable the traditional herbal medicine practice between both of our oriental culture;otherwise they will not last till now and use beyond India and China,but among other modern countries like Singapore,Japan,south Korea,Taiwan and lots of countries in the Far East region of the world as well as other parts of the world not being mentioned.
But if you look at the current herbal medicine formulations closely and compare thousands years ago,for example ,the bible of Chinese herbal medicine called" The classification  of the origin of herbs" written a couple thousands years ago. You will notice the herbal formulas are continuing to evolve and change  for a better treatment outcome.And now as you may know already the herbal medicines are adapting the western method to simplify the method of delivery--from cooking out a concoction to making  them into extracts ,granuals or put the solid ingredient after purification in to capsule form for easy compliance of the patients. But the efficacy of the herbal alone or in combination is difficult to prove and I think that is one of the reason that the Herbal medicine practice is ,in my research opinion,a continuation of clinical trial over a much longer  period for each patient who are on herbal medicine and most of them will take other additional supplements as they see fit.
I personally used Chinese herbal medicines that I know of maybe of proven value,more or less like the oleander extract you have done research on. But I know full well that herbal medicine may only work for some and not for the others and  the effectiveness may be marginal on treating cancer, but definitely have its value on the complimentary side of the spectrum., decrease the side effects of chemotherapy,provide harmony and well being comfort as a whole to the human body. . Therefore the main reason for me to use herbal is " for me as an experiment only to prove whether that herbal works for me or not- a one man clinical trial." The same as I had done to see how fast and how big my tumor can grow in a 10-12 month  period.
I am a medical professional who knows a bit more about the inner workings, their goal , function and the responsibility of FDA to the entire world than many of the average people in the States . So I will restricted my comment with regard to your view of the FDA . But I have no problem to believe that ,without the careful planning ,review , mandate of laws and other legal matters to guard against false claims of treatments efficacy.without tens of thousands of science researchers and clinicians to formulated clinical trials from a single chemical compound which studied and picked out from thousands possible chemical compounds; and make that single  chemical compound go thru years of clinical trails from phase 1 to phase 4,then in my opinion, there will be no effective treatments,medical devices and drugs to be invented and we will be back in the middle age medical practice again ,crude and painful.
furthermore, under the current system ,if it fails to meet the end points of that study, then the big pharma will lose a lot of money but they will start again,most of the time, to find another compound out of the tens or thousands chemicals  until the efficacy of that chemical compound is known, then FDA will be involved for approval it to become a drug. . It truly is  not a single person' s effort but involved thousands. Therefore the comment of" rigorous testing" is not only appropriate but always  adopted by the FDA, as well as universities , medical centers and the Big and Small pharmaceutical companies which are involved.

.I believe both of  our intentions are good for the forum otherwise we both will not spend this much time for such a horrible disease. I wish I can be as lucky as your dad to achieve such longevity  since I am also a cholangiocarcinoma  patient.
BTW,I did take a look about herbs similiar to oleander in my Chinese herbal manual, it's medicinal  property is on the " cool side" and I am belong to the cool side; according to the Chinese herbal practitioner ( TCM),  it may be good for me if I take oleander with other "warmer" medicinal property herbs like Korea  gingsing or Juju bean among others to balance my " positive and negetive energy " if I want to try oleander extract. (ps. for patients and other caregivers who are not familiar with herbal medicine, read the below link before considering using oleander.)
You are a good son  to your father and care about other people as well, and we appreciate your contribution to this forum.
God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Nerium Oleander Extract

Hi Percy, I find this all so very interesting, although I kind of go along with the Scientific approach. With that said, my wish is for you to keep up your one man trial and in another 50 years give us the results!

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: Nerium Oleander Extract

Hi, Lainy
I will promise you this, if I can last that long with this disease, i will be turned into a medical display somewhere in Mayo .clinic or in the freezer in the basement for them to dissect and learn about CCA . If so, I cannot come to your place to cook and stir fry  a sliced  bitter cucumber or melon with diced or sliced chicken or salmon for you. Yummy dish but required special taste buds.
Take good care of yourself.
God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Nerium Oleander Extract

Hi,
here is the link from american cancer society on oleander.

http://www.cancer.org/treatment/treatme … ander-leaf

God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Nerium Oleander Extract

Zowie, Percy! Thanks for this post. Scary, but interesting.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: Nerium Oleander Extract

Humblest greetings to you all i hope everyone is as well as they can be. My intentions here are not to promote anything especially herbal remedies. My advice is that we are in the age of information therefore anything with due diligence can be researched. One oviously has to be aware of misinformation and propaganda. MD Anderson have done testing with oleander extract. As to FDA and Big Pharma that is just too big of a topic to talk about. Off label arketing done by Big Pharma is illegal but is still practiced, fundamentally for an industry there to aid humanity (is it, isn't it, i don't know) puts up a big red flag for me. Just recently ive read about anti depressants being linked with a lot of unimaginable behaviours and crimes. The british Medical Joural will only allow papers to be published if all research data is provided, this is a relativley new practice, as before companies would only publish favourable outcomes to their studies regardless of whether the negative outnumbered the positive. So what im trying to say is, one must use their best judgement or rely on the best judgement of others.

15 (edited by marions Thu, 04 Apr 2013 19:05:40)

Re: Nerium Oleander Extract

This discussion forum provides the perfect venue for comments of any kind hence; I appreciate your thought provoking contributions to this site.  In re: to off label drugs:  Pharma generates a majority of revenue from off label drug usage.  Physicians are able to prescribe medications based on their expert opinions however; Pharma is not allowed to market as such.  But, as you well know, the rules are broken often. 
Like you, I believe that life saving drugs should be developed for humanity reasons only however; these industries are businesses and they provide something we desperately need. 
Much of the information published especially via the internet is questionable at best, but as you say, it is difficult for a layperson to distinguish the relevant from the non-relevant.  Therefore, it is best to focus on those studies peer-reviewed and presented by reputable organizations and then follow-up with the treating physicians. 
And, you are so right, dear NarinderSing, ultimately we have to make a decision based on what we believe is best for our personal situation. 
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Nerium Oleander Extract

I don't care what anyone says but I firmly believe that there's NO cure for Bile Duct Cancer for now, not even Nerium Oleander Extract.  At the same token, I believe that there has been a cure for cancer for many years but they have failed to advise the public because the pharmaceutical companies would lose a great amount of money.  Chemo costs a fortune as well as other medications related to cancer treatments. 

What a shame to watch and hear of so many people dying of Cancer.  My mother died of Bile Duct Cancer and I will never forget it.