My answer to this topic is, if you and your caregiver can wait for 5-7 more years and you(the patient him/herself) wants to fight it out and will endure the side effects that the treatments dish out for you; then please keep up with the current knowledge to decide when to give in or give up.
The "5-7 years" time frame is given by Dr. Hahn who is a medical oncologist and runs the The Center For Cancer Genome Discovery Lab, one of the largest 24/7 genetic lab in the States, and is the Deputy Chief Scientific Officer at Dana-Farber Cancer Institute. He said his lab has discovered several new oncogenes as well as targets that will pave the way for new therapeutic approaches.The approaches ,the models and the tools that his lab had pioneered and developed have already become widely used worldwide to discover and validate molecularly targeted cancer therapies.
Dr. Hahn indicated that 5-7 years from now, the field of chemotherapy and targeted therapy will be a lot more precise and the treatment approach will be much more specific and less adverse drug reaction cause by the new crops of new drugs that will be on the markets soon.
The same sentiment was also echoed by Peter Smith,PhD, the executive director of Drug Discovery Biology at H3 BioMedicine where he is responsible for overseeing drug discovery and translational medicine efforts of lead projects. He also works on identifying novel mechanisms of resistance that impacted clinical trial design and involved in additional drug discovery effort. His research efforts resulted in the design and initiation of several clinical trials . But he also suggested if all the labs can share each lab's data as an open source with each other , and bring the patients , researchers, clinicians and scientists to work together then things will go much faster and sooner.
In short, cooperation among different groups and patient education are the keys for speedy new drug development in targeted therapy and biomarker development.
So, just try to give all of you an up- date development and/or difficulties on the frontier of new drug development and you decide what you will do with this information in the future if needed.
The above information was from the CanLiv symposium that I had attended on April 5, 2013 in Washington DC.
Personally,the above information somewhat changed my mind about what I had decided . And I will keep an open eye on both the new drug development and the new interest in immunology related treatment for cancer to make my final decision on my condition at that moment when the time is come.
Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.