1 (edited by PCL1029 Sun, 21 Apr 2013 08:18:17)

Topic: IRE (Irreversible Electroporation ) To Treat Tumor Near difficult Area

Hi, Everyone,

Below is IRE treatment model in Human.(April 14-18 2013 Society of Interventional Radiology Convention.)

http://medicalxpress.com/news/2013-04-e … treat.html

for a more deeper approach.click the link below.(very easy to understand:
and choose the slide presentation on this subject.(2013 SIR Annual Scientific Meeting Press Releases: Sunday, April 14)

Electrical pulse treatment pokes holes in hard-to-treat tumors;
New minimally invasive therapy safely treats complex cancers, leaves healthy tissues intact
(SLIDES)

http://www.sirweb.org/news/ASM13_pressroom.shtml

Below is an older info but still useful in understanding IRE in animal model.

We observed cell ablation to the margin of the treated lesion with several cells thickness resolution. There appears to be complete ablation to the
margin of blood vessels without compromising the functionality of the blood vessels, which suggests that IRE is a promising method for treatment of tumors near blood vessels (a significant challenge with current ablation methods). Consistent with the mechanism of action of IRE on the cell membrane only, we show that the structure of bile ducts, blood vessels,
and connective tissues remains intact with IRE.
We report extremely rapid resolution of lesions, within two weeks, which is consistent with retention of vasculature.
We also document tentative evidence for an immunological response to the ablated tissue. Last, we show that mathematical predictions with the Laplace equation can be used in treatment planning.
The IRE tissue ablation technique, as characterized in this report, may become an important new tool in the surgeon armamentarium.--www.tcrt.org

I believe it is using in human now in trials.

God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: IRE (Irreversible Electroporation ) To Treat Tumor Near difficult Area

Wow, Percy, this sounds exciting. Good news that new trials seem to be popping up more often. Looks like your prediction of cures in 5 - 7 years may very well come true. Thanks so much for this article.

Teddy ~In our hearts forever~ATTITUDE is EVERYTHING
Any suggestion I offer is intended as friendly advice based solely on my own experience. Please consult your doctor for professional guidance.

Re: IRE (Irreversible Electroporation ) To Treat Tumor Near difficult Area

Hi, Lainy,

You are always welcome. thanks.

God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: IRE (Irreversible Electroporation ) To Treat Tumor Near difficult Area

Hi Percy,

Thanks once again for such great information.  I see a doctor at Sloan (where I am being treated) was one of the presenters at the IR conference where they showed the results of the preliminary study of IRE.  The results look very promising.  Looks like they'll be doing a larger clinical trial.  I will follow this closely just in case my SBRT treatment doesn't work.  It's good to know there's a lot of movement towards other treatment options for CC down the road.  Makes me feel more positive that I can stay alive a lot longer with this disease.

Can't thank you enough for your tireless research work!

Mary

Re: IRE (Irreversible Electroporation ) To Treat Tumor Near difficult Area

thank you Percy. Most interesting.