I have been on gem/cis off and on for about a year and a half and have recently had some neuropathy in my feet and hearing problems so I asked to try something else. It's an emotional decision as the gem/cis has been keeping the cancer stable but I think my body has had enough Cisplatin. I start on Gemzar/Xeloda tomorrow 2 weeks on-1 week off. I took Xeloda for 6 weeks when I had radiation and did not have any problems so I am hoping that holds true this time. By reading the posts I know many of you have been on this combination, so if you have any words of wisdom or tips I would love to hear from you!