I can't comment from experience, but I am also looking into this therapy area (my wife has unresectable ICC).
One promising chemoembolization therapy I found was Drug-Eluting Beads with IRInotecan (DEB-IRI).
Here is a presentation that discusses the procedure:
http://www.biocompatibles.com/uploads/d … /APP20.pdf
A research paper describing some of the results is here:
http://www.stencor.com.br/ingles/arquiv … eraphy.pdf
The paper reports on results from this procedure on 24 patients. The paper describes the number of partial responses and median survival. The part of the results that caught my eye were:
"Three patients were downstaged to resection and
underwent subsequent hepatectomy with radiofrequency
ablation. Three patients showed a complete response with
100% loss of positron emission tomography scan activity.
Of these, 1 patient remains free of disease (follow-up time,
33.8 months) and 2 patients are alive with disease (followup
time, 33.3 and 80 months)."
***Although I can't figure out why the abstract claims only 1 patient was downgraded to resection...
Here is a clinical trial evaluating the procedure:
please understand that I am not a doctor and I am just doing my own research the same as you. As such, I can't really say whether this is a good idea or not for you. However, I did want to make sure you knew it was out there.