Thanks Gavin for the info.
Rebecca ,if your father in law has liver metastasizes, I will get a 2nd opinion from the liver surgeon and also from an interventional radiologist to see whether the tumors can be removed first ,then will talk with the medical oncologist for adjuvant chemotherapy or targeted therapy. MASS GENERAL,JOHN HOPKINS SLOAN-Kettering are great hospitals just to name a few near you.
First line chemo therapy include. GEM/CIS, GEMOX, 5FU/CIS,FOLFOX among others, second line including GTX,TARCEVA+Avastin, Sorafinib ,Rituximab etc.
Below is a link about systemic chemotherapy and targeted therapy in general, so you can have some ideas.
http://www.cholangiocarcinoma.org/punbb … hp?id=7843
Clinical trials are worth it depends on each individual case and the availablity and suitability to the patient, it is best to ask referral from your current oncologist if he/she opens to the idea.
Please check out the clinical trials on our web site under the cholangiocarcinoma on the top , open and click clinical trials and you will have some idea whether your father can go .
Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.