Topic: Platelets too low for Cis?

Hi all, i'm just emailing with a query re platelets being too low for chemo. My mum had her first dose of chemo last week (Gem/Cis) but has just had her bloods taken and she is only having Gem today as her platelets are too low for the Cis. I'm just wondering if this happens often, and what this means?

Re: Platelets too low for Cis?

Hi,

just some info. if interested:

Gemzar alone: 24%(all grades) will have thrombocytopenia(low platelet count) .for grade 3 and 4 (more serious) ,the % is 4%.
cisplatin alone: 30%;for grade 3 / 4 ,the %= 3%.
Combined GEM/CIS regimen when compare to cisplatin  alone in one study=85%(all grades) to 13%(all grades)
God bless.

Please know that my personal opinion is not intended nor implied to be a substitute for professional medical advice. If  provided, information are for educational purposes.Consult doctor is a MUST for changing of treatment plans.

Re: Platelets too low for Cis?

I had 2 rounds of Gem/Cis and had to stop because my platelets were too low also.  Now I am on Oxaliplatin & Xeloda.  I am on round 2 of this now.  We just have to keep on trying & hope that it works!

Re: Platelets too low for Cis?

Jules...it happens frequently.  Platelets may be up for the upcoming session and/or doctor may prescribe something to help raise the platelet count.
Hang in there.
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Platelets too low for Cis?

Hey, thanks for the responses. It's hard to know what to worry about and what is okay at the beginning. We're so new to all of this! It's good to hear that this is a regular thing and hopefully mum's platelets will be back on track for the next round. Hugs, Jules.

Re: Platelets too low for Cis?

My wife is on Gem/Cis and started have low blood counts after 4-5 cycles.  The Dr. proscribed Neupagen shots after each treatment.

The sequence is like this:
Day 1 treatment
Day 2 shot
Day 3 shot
Day 4 shot

Day 8 treatment
Day 9 shot
Day 10 shot
Day 11 shot

This regime has dealt with the problem.

Good luck,

Jason

Re: Platelets too low for Cis?

Thanks Jason, it's good to know that it can be resolved. We were just a bit worried as it's happened so early on in treatment but hopefully this is just a minor setback.

Re: Platelets too low for Cis?

I'm quite a bit further along but thought you might like to know .... after months of cis/gem then surgery and y-90, my platelets have been around 50 to 80 for six months now and are never coming back on their own. So I am having an embolization of the spleen so I can go back on chemo or get into a trial. Apparently that can kick out many platelets, if your spleen is enlarged, which it is in many liver disease patients.