Topic: Ca19-9 going up

Hi, My husband is 2 months post radiation and xeloda. He had surgery and Gemzar before that starting in February 2013. He just had a scan that did not indicate any metastatic growth but his Ca19-9 was up to 67. Right after his surgery, his Ca19-9 was 125. After the Gemzar, it was 25. We have an appointment to redo the bloodwork in a two weeks. Assuming the reading was accurate, what are your expectations of the possible reactions to this elevation? Will they start chemo again? Which drug might they use? What might be the duration? Is there the possibility that they wait till the scan shows something positive before they start treatment? Thanks in advance for your thoughts.

Re: Ca19-9 going up

It is my experience and that of most of the members that CA19-9 used used as a loose basis.
My onc pays little attention to the numbers. The fact that it is up to 67 from 25 is something to be noted. If the scan was clear, I would say either your team will schedule a PET scan or rescan in 8 weeks. If they don't mention a PET, you should ask. Depending on insurance, you may be able to get one with no problems. If you have AETNA or any similar (backwards) insurance, you may have to fight for it.
Ask your onc what he/she thinks.

KrisJ
"Don't just have minutes in the day; have moments in time."
Any opinions I give are based on personal experiences, and are not based on medical knowledge. I strongly suggest receiving medical care and opinions.

Re: Ca19-9 going up

Jane....tumor markers on it's own are of little value rather, it is the up or down trend that physicians will watch closely. Infections, for example, can cause these markers to rise also.  Assuming that the markers rise again, then physicians will look for other ways of detecting possible tumor growths and may recommend: interventional radiation, systemic chemotherapy, or a clinical trial.  Fingers are crossed for the upcoming blood test to reveal nothing out of the ordinary.
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER

Re: Ca19-9 going up

My mom's tumor markers were never high....even when she was newly diagnosed with a 7cm tumor...I see many post about the markers being good or bad but I am wondering how accurate they could be??

Re: Ca19-9 going up

Daisy....About 10% of the Caucasian population the CA 19-9 do not have a particular protein (Lewis antigen) Even those with large tumors don't see a rise in the CA 19-9.   
Hugs,
Marion

THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER