Topic: Induction of apoptosis in cholangiocarcinoma by an andrographolide ana

Induction of apoptosis in cholangiocarcinoma by an andrographolide analogue is mediated through topoisomerase II alpha inhibition.

"These results suggest that andrographolide analogue 3A.1, a novel topo II inhibitor, has significant potential to be developed as a new anticancer agent for the treatment of CCA."

http://www.ncbi.nlm.nih.gov/pubmed/24360936

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