I’ve been to this forum many times. Thanks to all for sharing their experiences. I need help for my mother.
She was diagnosed last May with extra-hepatic cholangiocarcinoma centered around the gall-bladder. The tumor is small (2 cm x 2 cm). There was no evidence of tumor spread. They didn't perform a surgery to remove the tumor because it involved the blood vessels in that area. She started Chemotherapy (Gemcitabine and Cisplatin). She finished five and a half rounds. Then she had radiation with oral chemotherapy Xeloda. She finished six weeks of radiation in November. She hasn’t had treatments since then.
The scan they did in August during the chemotherapy showed that the tumor had shrunk, but still not removable. The scan she had in late December showed new nodules in her abdominal cavity. They repeated the scan at the end of January to monitor the new nodules. The nodules increased in number and in size.
The oncologist offered us three options. She could do nothing. She could do second chemotherapy (Xeloda + Oxaliplatin). She could do a clinical trial. He didn’t recommend doing a clinical trial because the chance of an experimental drug working is less than the standard chemotherapy.
What is the best course? I think doing standard chemotherapy or a trial. How soon should we start? Is there an on-going/upcoming trial that’s been beneficial? Is the recommended chemotherapy harsh?
Thank you very much for your help.